@article{1b065b44d5f24bdc81265ab0ae876450,
title = "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events",
abstract = "Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events.",
keywords = "Ankle brachial index, cardiovascular diseases, risk assessment",
author = "Fowkes, {F. G.R.} and Murray, {G. D.} and I. Butcher and Folsom, {A. R.} and Hirsch, {A. T.} and Couper, {D. J.} and G. Debacker and M. Kornitzer and Newman, {A. B.} and Sutton-Tyrrell, {K. C.} and M. Cushman and Lee, {A. J.} and Price, {J. F.} and D'Agostino, {R. B.} and Murabito, {J. M.} and Norman, {P. E.} and Masaki, {K. H.} and Bouter, {L. M.} and Heine, {R. J.} and Stehouwer, {C. D.A.} and McDermott, {M. M.} and Stoffers, {H. E.J.H.} and Knottnerus, {J. A.} and M. Ogren and B. Hedblad and W. Koenig and C. Meisinger and Cauley, {J. A.} and Franco, {O. H.} and Hunink, {M. G.M.} and A. Hofman and Witteman, {J. C.} and Criqui, {M. H.} and Langer, {R. D.} and Hiatt, {W. R.} and Hamman, {R. F.}",
note = "Funding Information: The ARIC study was supported by the National Heart, Lung, and Blood Institute (contracts HHSN268201100005C, -06C, -07C, -08C, -09C, -10C, -11C, and -12C). ",
year = "2014",
month = mar,
doi = "10.1177/2047487313516564",
language = "English (US)",
volume = "21",
pages = "310--320",
journal = "European Journal of Preventive Cardiology",
issn = "2047-4873",
publisher = "SAGE Publications Ltd",
number = "3",
}