Development from the fertilized egg to the three germ layers and its relevance to signaling and lineage commitment of embryonic stem cells

Paul Burridge; Kenneth R. Boheler

doi:10.1201/b16487

Development from the fertilized egg to the three germ layers and its relevance to signaling and lineage commitment of embryonic stem cells

Paul Burridge, Kenneth R. Boheler^*

^*Corresponding author for this work

Pharmacology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

In this chapter we cover developmental biology of murine development from the fertilized egg to lineage commitment and specification of the three germ layers. Post-fertilization processes including pluripotency, pre-and post-implantation development and axis specification are discussed in detail. We go on to discuss the role of the Tgf-Β, Nodal, Activin, Bmp, Fgf.

Original language	English (US)
Title of host publication	Stem Cells
Subtitle of host publication	From Basic Research to Therapy, Volume 1: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms
Publisher	CRC Press
Pages	151-184
Number of pages	34
ISBN (Electronic)	9781482207767
ISBN (Print)	9781482207750
DOIs	https://doi.org/10.1201/b16487
State	Published - Jan 1 2014

ASJC Scopus subject areas

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

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Burridge, P., & Boheler, K. R. (2014). Development from the fertilized egg to the three germ layers and its relevance to signaling and lineage commitment of embryonic stem cells. In Stem Cells: From Basic Research to Therapy, Volume 1: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms (pp. 151-184). CRC Press. https://doi.org/10.1201/b16487

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Development from the fertilized egg to the three germ layers and its relevance to signaling and lineage commitment of embryonic stem cells. / Burridge, Paul; Boheler, Kenneth R.

Stem Cells: From Basic Research to Therapy, Volume 1: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms. CRC Press, 2014. p. 151-184.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Development from the fertilized egg to the three germ layers and its relevance to signaling and lineage commitment of embryonic stem cells

Abstract

ASJC Scopus subject areas

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