In this chapter we cover developmental biology of murine development from the fertilized egg to lineage commitment and specification of the three germ layers. Post-fertilization processes including pluripotency, pre-and post-implantation development and axis specification are discussed in detail. We go on to discuss the role of the Tgf-Β, Nodal, Activin, Bmp, Fgf.
|Original language||English (US)|
|Title of host publication||Stem Cells|
|Subtitle of host publication||From Basic Research to Therapy, Volume 1: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms|
|Number of pages||34|
|State||Published - Jan 1 2014|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)