Abstract
In this chapter we cover developmental biology of murine development from the fertilized egg to lineage commitment and specification of the three germ layers. Post-fertilization processes including pluripotency, pre-and post-implantation development and axis specification are discussed in detail. We go on to discuss the role of the Tgf-Β, Nodal, Activin, Bmp, Fgf.
Original language | English (US) |
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Title of host publication | Stem Cells |
Subtitle of host publication | From Basic Research to Therapy, Volume 1: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms |
Publisher | CRC Press |
Pages | 151-184 |
Number of pages | 34 |
ISBN (Electronic) | 9781482207767 |
ISBN (Print) | 9781482207750 |
DOIs | |
State | Published - Jan 1 2014 |
ASJC Scopus subject areas
- General Medicine
- General Biochemistry, Genetics and Molecular Biology