Development of nonspecific interstitial pneumonitis associated with long-term treatment of primary pulmonary hypertension with prostacyclin

Steven Kesten; John Dainauskas; Vallerie McLaughlin; Stuart Rich

doi:10.1378/chest.116.2.566

Development of nonspecific interstitial pneumonitis associated with long-term treatment of primary pulmonary hypertension with prostacyclin

Steven Kesten^*, John Dainauskas, Vallerie McLaughlin, Stuart Rich

^*Corresponding author for this work

Medicine, Cardiology Division

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A young woman with primary pulmonary hypertension presented with interstitial lung disease approximately 5 years after successful treatment with IV prostacyclin. The pathology was consistent with nonspecific interstitial pneumonitis and was unresponsive to steroids and immunosuppressive medications. We speculate that further cases of this syndrome may be reported as more patients are living beyond 5 years with prostacyclin.

Original language	English (US)
Pages (from-to)	566-569
Number of pages	4
Journal	CHEST
Volume	116
Issue number	2
DOIs	https://doi.org/10.1378/chest.116.2.566
State	Published - 1999

Keywords

Interstitial lung disease
Primary pulmonary hypertension
Prostacyclin

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine
Pulmonary and Respiratory Medicine

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10.1378/chest.116.2.566

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title = "Development of nonspecific interstitial pneumonitis associated with long-term treatment of primary pulmonary hypertension with prostacyclin",

abstract = "A young woman with primary pulmonary hypertension presented with interstitial lung disease approximately 5 years after successful treatment with IV prostacyclin. The pathology was consistent with nonspecific interstitial pneumonitis and was unresponsive to steroids and immunosuppressive medications. We speculate that further cases of this syndrome may be reported as more patients are living beyond 5 years with prostacyclin.",

keywords = "Interstitial lung disease, Primary pulmonary hypertension, Prostacyclin",

author = "Steven Kesten and John Dainauskas and Vallerie McLaughlin and Stuart Rich",

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AU - Kesten, Steven

AU - Dainauskas, John

AU - McLaughlin, Vallerie

AU - Rich, Stuart

PY - 1999

Y1 - 1999

N2 - A young woman with primary pulmonary hypertension presented with interstitial lung disease approximately 5 years after successful treatment with IV prostacyclin. The pathology was consistent with nonspecific interstitial pneumonitis and was unresponsive to steroids and immunosuppressive medications. We speculate that further cases of this syndrome may be reported as more patients are living beyond 5 years with prostacyclin.

AB - A young woman with primary pulmonary hypertension presented with interstitial lung disease approximately 5 years after successful treatment with IV prostacyclin. The pathology was consistent with nonspecific interstitial pneumonitis and was unresponsive to steroids and immunosuppressive medications. We speculate that further cases of this syndrome may be reported as more patients are living beyond 5 years with prostacyclin.

KW - Interstitial lung disease

KW - Primary pulmonary hypertension

KW - Prostacyclin

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Development of nonspecific interstitial pneumonitis associated with long-term treatment of primary pulmonary hypertension with prostacyclin

Abstract

Keywords

ASJC Scopus subject areas

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