Development of regenerative mesenchymal stem cell-seeded scaffolds for bladder augmentation

Madeleine M. Goedegebuure, Larry Wang, Arun K. Sharma

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The lower urinary tract (LUT) is a muscular system comprising the bladder, an outflow tract composed of the bladder neck, urethra, and internal and external urethral sphincters. Estimates from 2008 indicate that 45.2% of people older than 20 have been affected with at least one instance of LUT disease symptoms and a predicted 2.3 billion people were affected in 2018. Due to the critical role of the LUT in waste removal, there is a significant need to provide treatments that can help people maintain healthy LUT function.

Original languageEnglish (US)
Title of host publicationScientific Advances in Reconstructive Urology and Tissue Engineering
PublisherElsevier
Pages25-50
Number of pages26
ISBN (Electronic)9780323911993
ISBN (Print)9780323915205
DOIs
StatePublished - Jan 1 2022

Keywords

  • Lower urinary tract
  • bladder augmentation
  • chronic kidney disease
  • hematopoietic stem cell
  • mesenchymal stem cell
  • muscular system
  • regenerative engineering

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology

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