Development of regenerative mesenchymal stem cell-seeded scaffolds for bladder augmentation

Madeleine M. Goedegebuure, Larry Wang, Arun K. Sharma

Research output: Chapter in Book/Report/Conference proceedingChapter


The lower urinary tract (LUT) is a muscular system comprising the bladder, an outflow tract composed of the bladder neck, urethra, and internal and external urethral sphincters. Estimates from 2008 indicate that 45.2% of people older than 20 have been affected with at least one instance of LUT disease symptoms and a predicted 2.3 billion people were affected in 2018. Due to the critical role of the LUT in waste removal, there is a significant need to provide treatments that can help people maintain healthy LUT function.

Original languageEnglish (US)
Title of host publicationScientific Advances in Reconstructive Urology and Tissue Engineering
Number of pages26
ISBN (Electronic)9780323911993
ISBN (Print)9780323915205
StatePublished - Jan 1 2022


  • Lower urinary tract
  • bladder augmentation
  • chronic kidney disease
  • hematopoietic stem cell
  • mesenchymal stem cell
  • muscular system
  • regenerative engineering

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology


Dive into the research topics of 'Development of regenerative mesenchymal stem cell-seeded scaffolds for bladder augmentation'. Together they form a unique fingerprint.

Cite this