TY - GEN
T1 - Device Configuration and Patient's Body Composition Significantly Affect RF Heating of Deep Brain Stimulation Implants during MRI
T2 - 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020
AU - Bhusal, Bhumi
AU - Nguyen, Bach T.
AU - Vu, Jasmine
AU - Elahi, Behzad
AU - Rosenow, Joshua
AU - Nolt, Mark J.
AU - Pilitsis, Julie
AU - Dimarzio, Marisa
AU - Golestanirad, Laleh
N1 - Publisher Copyright:
© 2020 IEEE.
PY - 2020/7
Y1 - 2020/7
N2 - Patients with deep brain stimulation (DBS) devices have limited access to magnetic resonance imaging (MRI) due to safety concerns associated with RF heating generated around the implant. The problem of predicting RF heating of conductive leads is complex with a large parameter space and several interplaying factors. Recently however, off-label use of MRI in patients with DBS devices has been reported based on limited safety assessments, raising the concern that potentially dangerous scenarios may have been overlooked. In this work, we present results of a systematic assessment of RF heating of a commercial DBS device during MRI at 1.5T and 3T, taking into account the effect of device configuration, imaging landmark, and patient's body composition. Ninety-six (96) RF heating measurements were performed using anthropomorphic phantoms implanted with a full DBS system. We evaluated eight clinically relevant device configurations, implanted in phantoms with different material compositions, and imaged at three different landmarks (head, shoulder, and lower chest) in 1.5 T and 3T scanners. We observed a substantial fluctuation in the RF heating depending on phantom's composition and device configuration. RF heating in the brain-mimicking gel varied from 0.1°C to 12°C during 1.5 T MRI and from <0.1°C to 4.5°C during 3T MRI. We also observed that certain device configurations consistently reduced RF heating across different phantom compositions, imaging landmarks, and MRI transmit frequencies.
AB - Patients with deep brain stimulation (DBS) devices have limited access to magnetic resonance imaging (MRI) due to safety concerns associated with RF heating generated around the implant. The problem of predicting RF heating of conductive leads is complex with a large parameter space and several interplaying factors. Recently however, off-label use of MRI in patients with DBS devices has been reported based on limited safety assessments, raising the concern that potentially dangerous scenarios may have been overlooked. In this work, we present results of a systematic assessment of RF heating of a commercial DBS device during MRI at 1.5T and 3T, taking into account the effect of device configuration, imaging landmark, and patient's body composition. Ninety-six (96) RF heating measurements were performed using anthropomorphic phantoms implanted with a full DBS system. We evaluated eight clinically relevant device configurations, implanted in phantoms with different material compositions, and imaged at three different landmarks (head, shoulder, and lower chest) in 1.5 T and 3T scanners. We observed a substantial fluctuation in the RF heating depending on phantom's composition and device configuration. RF heating in the brain-mimicking gel varied from 0.1°C to 12°C during 1.5 T MRI and from <0.1°C to 4.5°C during 3T MRI. We also observed that certain device configurations consistently reduced RF heating across different phantom compositions, imaging landmarks, and MRI transmit frequencies.
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U2 - 10.1109/EMBC44109.2020.9175833
DO - 10.1109/EMBC44109.2020.9175833
M3 - Conference contribution
C2 - 33019155
AN - SCOPUS:85091004199
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 5192
EP - 5197
BT - 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 20 July 2020 through 24 July 2020
ER -