Device exchange from Heartmate II to HeartWare HVAD

Rachel A. Beaupre*, Ahmed Alnajar, Tadahisa Sugiura, Brendan Chou, Harveen K. Lamba, Chitaru Kurihara, Masashi Kawabori, Andre C. Critsinelis, Adriana Santiago, Jeffrey A. Morgan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Despite technological advancements, pump durability and pump-related complications continue to affect and adversely impact the lives of patients with end-stage heart failure on left ventricular assist device (LVAD) support. In an attempt to avoid recurrent LVAD-related complications, there may be circumstances where it is clinically advantageous to exchange a patient's device from HeartMate II to HeartWare HVAD. However, there is a paucity of data that describes the safety and feasibility of such an approach. Objective: We present the largest single-center series of HeartMate II (HMII) to HeartWare (HVAD) device exchanges. Methods: A retrospective review of 11 patients who underwent HMII to HVAD exchange from 2012 to 2017 was conducted to evaluate patient characteristics, incidence of postoperative complications, and survival. Results: Eleven male patients (mean age 55 ± 14.4 years) underwent HMII to HVAD device exchange. One patient expired on postoperative day 7 secondary to sepsis. One patient was lost-to-follow-up after 23 months. An additional three patients died at 5, 7, and 24 months. Mean follow-up after device exchange was 1555 ± 311 days for the remaining six patients. None of the 11 study patients underwent LVAD explant, further device exchange, or heart transplant. Conclusion: Exchange of an HMII LVAD to an HVAD can be performed safely with acceptable perioperative morbidity and mortality.

Original languageEnglish (US)
Pages (from-to)1204-1207
Number of pages4
JournalJournal of Cardiac Surgery
Issue number11
StatePublished - Nov 1 2019


  • HeartMate II
  • HeartWare HVAD
  • LVAD
  • heart failure
  • mechanical circulatory support
  • ventricular assist device
  • ventricular assist device

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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