Dexamethasone nonsuppression in chronic schizophrenia

H. A. Whiteford*, S. J. Riney, R. A. Savala, J. G. Csernansky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

ABSTRACT— It has been suggested that dexamethasone nonsuppression in schizophrenia is related to the presence of negative symptoms. In a sample of chronic schizophrenic outpatients we could find no relationship between dexamethasone nonsuppression and negative symptoms. In addition nonsuppression was not related to depressive symptoms, anxiety or age. The cause of hypothalamic pituitary adrenal dysregulation in schizophrenic patients remains unclear.

Original languageEnglish (US)
Pages (from-to)58-62
Number of pages5
JournalActa Psychiatrica Scandinavica
Volume77
Issue number1
DOIs
StatePublished - Jan 1988

Funding

Keywords

  • DST
  • negative symptoms
  • schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

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