DGKE and atypical HUS

Susan E. Quaggin*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

28 Scopus citations

Abstract

A new study reports that recessive loss-of-function mutations in the gene encoding diacylglycerol kinase ε result in atypical hemolytic-uremic syndrome. Notably, mutations in DGKE are not associated with activation of the complement pathway, the only other identified cause of this disorder so far, and have important implications for patient management.

Original languageEnglish (US)
Pages (from-to)475-476
Number of pages2
JournalNature Genetics
Volume45
Issue number5
DOIs
StatePublished - May 1 2013

ASJC Scopus subject areas

  • Genetics

Fingerprint Dive into the research topics of 'DGKE and atypical HUS'. Together they form a unique fingerprint.

Cite this