Diabetes Mellitus and Pregnancy

P. Dandona, F. Boag, V. Fonseca, R. K. Menon, Ralph E. Bernstein, John M. Stronge, Michael E. Foley, M. Ivo Drury, John A. Colwell, Edgar O. Horger, Ronald K. Mayfield, Kay F. McFarland, Frances C. Wheeler, Norbert Freinkel, Sharon L. Dooley, Boyd E. Metzger

Research output: Contribution to journalLetter

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Abstract

To the Editor: The authoritative and scholarly review by Freinkel et al.1 (July 11 issue)1 on pregnancy and diabetes implies that both congenital malformations and early growth delay are the results of uncontrolled diabetes in early pregnancy, and that fetal macrosomia results from poor control during the third trimester. Our experience with continuous subcutaneous infusion of insulin during pregnancy does not totally substantiate the hypothesis that macrosomia results from uncontrolled diabetes in the latter part of pregnancy. In a series of eight pregnancies2,3 we were able to induce nearly perfect glucose homeostasis by means of continuous insulin infusion (mean fasting…

Original languageEnglish (US)
Pages (from-to)58-60
Number of pages3
JournalNew England Journal of Medicine
Volume314
Issue number1
DOIs
StatePublished - Jan 2 1986

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dandona, P., Boag, F., Fonseca, V., Menon, R. K., Bernstein, R. E., Stronge, J. M., Foley, M. E., Drury, M. I., Colwell, J. A., Horger, E. O., Mayfield, R. K., McFarland, K. F., Wheeler, F. C., Freinkel, N., Dooley, S. L., & Metzger, B. E. (1986). Diabetes Mellitus and Pregnancy. New England Journal of Medicine, 314(1), 58-60. https://doi.org/10.1056/NEJM198601023140116