Abstract
Type II diabetes mellitus is associated with peripheral insulin resistance and, in the great majority of cases, with obesity. The aggregation of i) obesity of the abdominal type, ii) hyperinsulinemia and insulin resistance, iii) hypertension, and iv) dyslipidemia, have been associated epidemiologically with increased cardiovascular risk. The relationship between the various manifestations of this <<insulin resistance syndrome>> remains uncertain. Data are presented herein demonstrating that involvement of the sympathetic nervous system, and perhaps the adrenal medulla, contribute to the pathogenesis of the various manifestations of the insulin resistance syndrome and, therefore, contribute to the increased cardiovascular risk that attends Type II diabetes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 153-158 |
| Number of pages | 6 |
| Journal | Cardiovascular Risk Factors |
| Volume | 3 |
| Issue number | 3 |
| State | Published - Jan 1 1993 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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Diabetes, obesity and hypertension : Role of insulin and the sympathetic nervous system. / Landsberg, Lewis.
In: Cardiovascular Risk Factors, Vol. 3, No. 3, 01.01.1993, p. 153-158.Research output: Contribution to journal › Short survey
TY - JOUR
T1 - Diabetes, obesity and hypertension
T2 - Role of insulin and the sympathetic nervous system
AU - Landsberg, Lewis
PY - 1993/1/1
Y1 - 1993/1/1
N2 - Type II diabetes mellitus is associated with peripheral insulin resistance and, in the great majority of cases, with obesity. The aggregation of i) obesity of the abdominal type, ii) hyperinsulinemia and insulin resistance, iii) hypertension, and iv) dyslipidemia, have been associated epidemiologically with increased cardiovascular risk. The relationship between the various manifestations of this <> remains uncertain. Data are presented herein demonstrating that involvement of the sympathetic nervous system, and perhaps the adrenal medulla, contribute to the pathogenesis of the various manifestations of the insulin resistance syndrome and, therefore, contribute to the increased cardiovascular risk that attends Type II diabetes.
AB - Type II diabetes mellitus is associated with peripheral insulin resistance and, in the great majority of cases, with obesity. The aggregation of i) obesity of the abdominal type, ii) hyperinsulinemia and insulin resistance, iii) hypertension, and iv) dyslipidemia, have been associated epidemiologically with increased cardiovascular risk. The relationship between the various manifestations of this <> remains uncertain. Data are presented herein demonstrating that involvement of the sympathetic nervous system, and perhaps the adrenal medulla, contribute to the pathogenesis of the various manifestations of the insulin resistance syndrome and, therefore, contribute to the increased cardiovascular risk that attends Type II diabetes.
UR - http://www.scopus.com/inward/record.url?scp=0027154112&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027154112&partnerID=8YFLogxK
M3 - Short survey
AN - SCOPUS:0027154112
VL - 3
SP - 153
EP - 158
JO - Cardiovascular Risk Factors
JF - Cardiovascular Risk Factors
SN - 1130-7501
IS - 3
ER -