Diabetic Control and Fetal Malformations

Michael Bergman, Stuart A. Newman, Timothy B. Seaton, Philip Felig, John L. Kitzmiller, Elliott K. Main, Jay S. Skyler, Edith Miller, James L. Mills, Boyd E. Metzger, Robert H. Knopp, Jerome H. Aarons, Lois Jovanovic-Peterson, Lewis B. Holmes, Joe Leigh Simpson

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


To the Editor: Mills and his colleagues in the Diabetes in Early Pregnancy Study (March 17 issue)1 contend that their data support no relation between increased malformation rates among infants of diabetic mothers and glycemic control during organogenesis. We suggest that very different conclusions can be drawn from the data they supply. Table 2 in their study shows that the incidence of “moderate to mild” malformations was virtually identical among infants of early-entry diabetic participants (10 of 347) and infants of control subjects (8 of 389). In contrast, the increase in the overall rate of malformations among the offspring of.

Original languageEnglish (US)
Pages (from-to)647-649
Number of pages3
JournalNew England Journal of Medicine
Issue number10
StatePublished - Sep 8 1988

ASJC Scopus subject areas

  • General Medicine


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