Diabetic Control and Fetal Malformations

Michael Bergman; Stuart A. Newman; Timothy B. Seaton; Philip Felig; John L. Kitzmiller; Elliott K. Main; Jay S. Skyler; Edith Miller; James L. Mills; Boyd E. Metzger; Robert H. Knopp; Jerome H. Aarons; Lois Jovanovic-Peterson; Lewis B. Holmes; Joe Leigh Simpson

doi:10.1056/NEJM198809083191011

Diabetic Control and Fetal Malformations

Michael Bergman, Stuart A. Newman, Timothy B. Seaton, Philip Felig, John L. Kitzmiller, Elliott K. Main, Jay S. Skyler, Edith Miller, James L. Mills, Boyd E. Metzger, Robert H. Knopp, Jerome H. Aarons, Lois Jovanovic-Peterson, Lewis B. Holmes, Joe Leigh Simpson

Medicine, Endocrinology Division

Research output: Contribution to journal › Letter › peer-review

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Abstract

To the Editor: Mills and his colleagues in the Diabetes in Early Pregnancy Study (March 17 issue)¹ contend that their data support no relation between increased malformation rates among infants of diabetic mothers and glycemic control during organogenesis. We suggest that very different conclusions can be drawn from the data they supply. Table 2 in their study shows that the incidence of “moderate to mild” malformations was virtually identical among infants of early-entry diabetic participants (10 of 347) and infants of control subjects (8 of 389). In contrast, the increase in the overall rate of malformations among the offspring of.

Original language	English (US)
Pages (from-to)	647-649
Number of pages	3
Journal	New England Journal of Medicine
Volume	319
Issue number	10
DOIs	https://doi.org/10.1056/NEJM198809083191011
State	Published - Sep 8 1988

ASJC Scopus subject areas

General Medicine

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10.1056/NEJM198809083191011

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Bergman, M., Newman, S. A., Seaton, T. B., Felig, P., Kitzmiller, J. L., Main, E. K., Skyler, J. S., Miller, E., Mills, J. L., Metzger, B. E., Knopp, R. H., Aarons, J. H., Jovanovic-Peterson, L., Holmes, L. B., & Simpson, J. L. (1988). Diabetic Control and Fetal Malformations. New England Journal of Medicine, 319(10), 647-649. https://doi.org/10.1056/NEJM198809083191011

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abstract = "To the Editor: Mills and his colleagues in the Diabetes in Early Pregnancy Study (March 17 issue)1 contend that their data support no relation between increased malformation rates among infants of diabetic mothers and glycemic control during organogenesis. We suggest that very different conclusions can be drawn from the data they supply. Table 2 in their study shows that the incidence of “moderate to mild” malformations was virtually identical among infants of early-entry diabetic participants (10 of 347) and infants of control subjects (8 of 389). In contrast, the increase in the overall rate of malformations among the offspring of.",

author = "Michael Bergman and Newman, {Stuart A.} and Seaton, {Timothy B.} and Philip Felig and Kitzmiller, {John L.} and Main, {Elliott K.} and Skyler, {Jay S.} and Edith Miller and Mills, {James L.} and Metzger, {Boyd E.} and Knopp, {Robert H.} and Aarons, {Jerome H.} and Lois Jovanovic-Peterson and Holmes, {Lewis B.} and Simpson, {Joe Leigh}",

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doi = "10.1056/NEJM198809083191011",

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T1 - Diabetic Control and Fetal Malformations

AU - Bergman, Michael

AU - Newman, Stuart A.

AU - Seaton, Timothy B.

AU - Felig, Philip

AU - Kitzmiller, John L.

AU - Main, Elliott K.

AU - Skyler, Jay S.

AU - Miller, Edith

AU - Mills, James L.

AU - Metzger, Boyd E.

AU - Knopp, Robert H.

AU - Aarons, Jerome H.

AU - Jovanovic-Peterson, Lois

AU - Holmes, Lewis B.

AU - Simpson, Joe Leigh

PY - 1988/9/8

Y1 - 1988/9/8

N2 - To the Editor: Mills and his colleagues in the Diabetes in Early Pregnancy Study (March 17 issue)1 contend that their data support no relation between increased malformation rates among infants of diabetic mothers and glycemic control during organogenesis. We suggest that very different conclusions can be drawn from the data they supply. Table 2 in their study shows that the incidence of “moderate to mild” malformations was virtually identical among infants of early-entry diabetic participants (10 of 347) and infants of control subjects (8 of 389). In contrast, the increase in the overall rate of malformations among the offspring of.

AB - To the Editor: Mills and his colleagues in the Diabetes in Early Pregnancy Study (March 17 issue)1 contend that their data support no relation between increased malformation rates among infants of diabetic mothers and glycemic control during organogenesis. We suggest that very different conclusions can be drawn from the data they supply. Table 2 in their study shows that the incidence of “moderate to mild” malformations was virtually identical among infants of early-entry diabetic participants (10 of 347) and infants of control subjects (8 of 389). In contrast, the increase in the overall rate of malformations among the offspring of.

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EP - 649

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 10

ER -

Diabetic Control and Fetal Malformations

Abstract

ASJC Scopus subject areas

UN SDGs

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