Diabetic kidney disease: A report from an ADA consensus conference

Katherine R. Tuttle, George L. Bakris, Rudolf W. Bilous, Jane L. Chiang*, Ian H. De Boer, Jordi Goldstein-Fuchs, Irl B. Hirsch, Kamyar Kalantar-Zadeh, Andrew S. Narva, Sankar D. Navaneethan, Joshua J. Neumiller, Uptal D. Patel, Robert E. Ratner, Adam T. Whaley-Connell, Mark E. Molitch

*Corresponding author for this work

Research output: Contribution to journalArticle

376 Scopus citations

Abstract

The incidence and prevalence of diabetes mellitus have grown significantly throughout the world, due primarily to the increase in type 2 diabetes. This overall increase in the number of people with diabetes has had a major impact on development of diabetic kidney disease (DKD), one of the most frequent complications of both types of diabetes. DKD is the leading cause of end-stage renal disease (ESRD), accounting for approximately 50% of cases in the developed world. Although incidence rates for ESRD attributable to DKD have recently stabilized, these rates continue to rise in high-risk groups such as middle-aged African Americans, Native Americans, and Hispanics. The costs of care for people with DKD are extraordinarily high. In the Medicare population alone, DKD-related expenditures among this mostly older group were nearly $25 billion in 2011. Due to the high human and societal costs, the Consensus Conference on Chronic Kidney Disease and Diabetes was convened by the American Diabetes Association in collaboration with theAmerican Society of Nephrology and the National Kidney Foundation to appraise issues regarding patient management, highlighting current practices and new directions. Major topic areas in DKD included 1) identification and monitoring, 2) cardiovascular disease and management of dyslipidemia, 3) hypertension and use of renin-angiotensin-aldosterone system blockade andmineralocorticoid receptor blockade, 4) glycemia measurement, hypoglycemia, and drug therapies, 5) nutrition and general care in advanced-stage chronic kidney disease, 6) children and adolescents, and 7)multidisciplinary approaches andmedical homemodels for health care delivery. This current state summary and research recommendations are designed to guide advances in care and the generation of new knowledge that willmeaningfully improve life for people with DKD.

Original languageEnglish (US)
Pages (from-to)2864-2883
Number of pages20
JournalDiabetes care
Volume37
Issue number10
DOIs
StatePublished - Oct 1 2014

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

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    Tuttle, K. R., Bakris, G. L., Bilous, R. W., Chiang, J. L., De Boer, I. H., Goldstein-Fuchs, J., Hirsch, I. B., Kalantar-Zadeh, K., Narva, A. S., Navaneethan, S. D., Neumiller, J. J., Patel, U. D., Ratner, R. E., Whaley-Connell, A. T., & Molitch, M. E. (2014). Diabetic kidney disease: A report from an ADA consensus conference. Diabetes care, 37(10), 2864-2883. https://doi.org/10.2337/dc14-1296