Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

A. T. Tharapel; M. L. Moretti; C. M. Meyers; L. P. Shulman; R. E. Tipton; J. B. Summitt; S. Elias; R. S. Wilroy; M. Epps; J. L. Simpson

doi:10.1055/s-2007-999483

Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

A. T. Tharapel, M. L. Moretti, C. M. Meyers, L. P. Shulman, R. E. Tipton, J. B. Summitt, S. Elias, R. S. Wilroy, M. Epps, J. L. Simpson

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multiple fetal anomalies and intrauterine growth retardation.

Original language	English (US)
Pages (from-to)	211-213
Number of pages	3
Journal	American journal of perinatology
Volume	7
Issue number	3
DOIs	https://doi.org/10.1055/s-2007-999483
State	Published - Jul 1990

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

Access to Document

10.1055/s-2007-999483

Cite this

Tharapel, A. T., Moretti, M. L., Meyers, C. M., Shulman, L. P., Tipton, R. E., Summitt, J. B., Elias, S., Wilroy, R. S., Epps, M., & Simpson, J. L. (1990). Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis. American journal of perinatology, 7(3), 211-213. https://doi.org/10.1055/s-2007-999483

Tharapel, A. T. ; Moretti, M. L. ; Meyers, C. M. ; Shulman, L. P. ; Tipton, R. E. ; Summitt, J. B. ; Elias, S. ; Wilroy, R. S. ; Epps, M. ; Simpson, J. L. / Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood : A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis. In: American journal of perinatology. 1990 ; Vol. 7, No. 3. pp. 211-213.

@article{2cc180842cce4b76a70b30e76b162163,

title = "Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis",

abstract = "Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multiple fetal anomalies and intrauterine growth retardation.",

author = "Tharapel, {A. T.} and Moretti, {M. L.} and Meyers, {C. M.} and Shulman, {L. P.} and Tipton, {R. E.} and Summitt, {J. B.} and S. Elias and Wilroy, {R. S.} and M. Epps and Simpson, {J. L.}",

year = "1990",

month = jul,

doi = "10.1055/s-2007-999483",

language = "English (US)",

volume = "7",

pages = "211--213",

journal = "American Journal of Perinatology",

issn = "0735-1631",

publisher = "Thieme Medical Publishers",

number = "3",

}

Tharapel, AT, Moretti, ML, Meyers, CM, Shulman, LP, Tipton, RE, Summitt, JB, Elias, S, Wilroy, RS, Epps, M & Simpson, JL 1990, 'Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis', American journal of perinatology, vol. 7, no. 3, pp. 211-213. https://doi.org/10.1055/s-2007-999483

Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood : A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis. / Tharapel, A. T.; Moretti, M. L.; Meyers, C. M.; Shulman, L. P.; Tipton, R. E.; Summitt, J. B.; Elias, S.; Wilroy, R. S.; Epps, M.; Simpson, J. L.

In: American journal of perinatology, Vol. 7, No. 3, 07.1990, p. 211-213.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood

T2 - A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

AU - Tharapel, A. T.

AU - Moretti, M. L.

AU - Meyers, C. M.

AU - Shulman, L. P.

AU - Tipton, R. E.

AU - Summitt, J. B.

AU - Elias, S.

AU - Wilroy, R. S.

AU - Epps, M.

AU - Simpson, J. L.

PY - 1990/7

Y1 - 1990/7

N2 - Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multiple fetal anomalies and intrauterine growth retardation.

AB - Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multiple fetal anomalies and intrauterine growth retardation.

UR - http://www.scopus.com/inward/record.url?scp=0025283081&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025283081&partnerID=8YFLogxK

U2 - 10.1055/s-2007-999483

DO - 10.1055/s-2007-999483

M3 - Article

C2 - 2372326

AN - SCOPUS:0025283081

VL - 7

SP - 211

EP - 213

JO - American Journal of Perinatology

JF - American Journal of Perinatology

SN - 0735-1631

IS - 3

ER -

Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this