Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

A. T. Tharapel, M. L. Moretti, C. M. Meyers, L. P. Shulman, R. E. Tipton, J. B. Summitt, S. Elias, R. S. Wilroy, M. Epps, J. L. Simpson

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multiple fetal anomalies and intrauterine growth retardation.

Original languageEnglish (US)
Pages (from-to)211-213
Number of pages3
JournalAmerican journal of perinatology
Volume7
Issue number3
DOIs
StatePublished - Jul 1990

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis'. Together they form a unique fingerprint.

Cite this