Diagnostic testing in glomerular disease

James J Paparello*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Glomerular diseases are among the hardest diseases to diagnose. They can affect multiple organs (and thereby cause multiple symptoms) or only the kidney. While specific diseases may have a "classic" presentation, the overlap among presentations is considerable, and often the only way to diagnose a glomerular disease is by a kidney biopsy. There are many diagnostic tests that can help diagnose a glomerular disease, and more are being identified. This chapter focuses on serologic and urine tests that can be used to help diagnose a glomerular disease. The main diagnostic considerations of the two glomerular syndromes, nephritic and nephrotic, are discussed individually. In a patient with nephritic or nephrotic syndrome, clinical judgment based on the presentation will always be needed to determine if other diagnostic tests should be sent off in place of a kidney biopsy or along with a kidney biopsy.

Original languageEnglish (US)
Title of host publicationGlomerulonephritis
PublisherSpringer International Publishing
Pages29-43
Number of pages15
ISBN (Electronic)9783319493794
ISBN (Print)9783319493787
DOIs
Publication statusPublished - Feb 26 2019

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Keywords

  • Anti-neutrophil cytoplasmic antibody (ANCA ab)
  • Glomerulonephritis
  • Nephritic syndrome
  • Nephrotic syndrome
  • Phospholipase A2 receptor 1 antibody (PLA2R1 ab)
  • suPAR

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Paparello, J. J. (2019). Diagnostic testing in glomerular disease. In Glomerulonephritis (pp. 29-43). Springer International Publishing. https://doi.org/10.1007/978-3-319-49379-4_3