Diagnostic value of refixation saccades in the Video Head Impulse Test (vHIT) in unilateral definite Meniere’s disease

Shreyas Bharadwaj, Michelle R. Petrak, Cammy M. Bahner, Laurin E. Sharp, Sara F. Mosey-Claycomb, Akihiro J. Matsuoka*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: We currently interpret the video Head Impulse Test (vHIT) results mainly based on the gain value. Aim: The purpose of this study is to evaluate vHIT results for both gain and re-fixation saccades on unilateral definite Meniere's disease (MD) subjects in comparison with normal healthy subjects. Materials and Methods: Forty unilateral definite MD subjects and age-matched healthy subjects were recruited. Pure tone audiometry, the caloric test, and the vHIT test were performed on MD subjects. The vHIT test was performed on healthy subjects. Results: The velocity regression gain (VRG) of the affected ear in patients with MD is significantly lower than of those in healthy subjects. The total percentage of refixation saccades is significantly higher in patients with MD when compared to healthy subjects. VRG values were not well-correlated with the percentage of refixation saccades. VRG asymmetry values are also not well-correlated with the percentage of unilateral canal weakness. A moderately stronger correlation between the percentage of refixation saccades and percentage of unilateral canal weakness, with an r2 of 0.474. Conclusions: The present study suggests that while VRGs are still a diagnostic parameter of detecting MD, the presence of refixation saccades can also have diagnostic value, especially with normal VRGs, in detecting MD.

Original languageEnglish (US)
Pages (from-to)537-543
Number of pages7
JournalActa Oto-Laryngologica
Volume140
Issue number7
DOIs
StatePublished - Jul 2 2020

Keywords

  • VOR
  • Vestibular diseases
  • balance
  • head impulse test
  • vHIT
  • vestibular
  • vestibular function tests
  • vestibulo-ocular reflex

ASJC Scopus subject areas

  • Otorhinolaryngology

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