Diet and coronary heart disease.

J. Stamler*

*Corresponding author for this work

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

This paper reviews key aspects of the relationship of diet to coronary heart disease, as demonstrated in epidemiologic and other research over the last 25 or more years. It summarizes the extensive findings that have demonstrated an etiologically significant association among dietary lipid, serum cholesterol, and coronary heart disease; between caloric imbalance and two of the major CHD risk factors, hypertension and hypercholesterolemia; on the relationship between habitual diet high in sodium and hypertension. It also reviews the data on the relationship of habitual dietary lipid intake of individuals within a population to the serum cholesterol and CHD risk of individuals, indicating that valid positive findings in this area are consistent with evidence from cross-population epidemiologic studies, controlled experiments on diet change in man, and findings from animal research. It delineates the controlled experiments on diet change in man, and findings from animal research. It delineates the methodological problems that have stood in the way of the sound elucidation of this matter, and of the similar ones making it difficult to fully resolve the issue of the relationship of habitual dietary sodium intake of individuals within a population to their blood pressure. It reviews recent findings on the relationship of diet, particularly dietary lipid and calorie balance, to fractions of plasma total cholesterol, i.e., LDL-cholesterol, VLDL-cholesterol, and HDL-cholesterol, and summarizes the evidence indicating that recommendations for improved nutrition in the United States--emphasizing sizable reduction in saturated fat and cholesterol intake, moderate decrease in intake of total fat and of refined and processed sugars, and of calories for overweight persons--produce changes in plasma lipidlipoprotein levels that are favorable in all respects. Finally, it summarizes the findings with respect to the marked decline in mortality from coronary heart disease, stroke, all cardiovascular diseases, and all causes in the United States from 1968 to 1978, and presents evidence indicating that improvements in life style (eating, smoking, and exercise habits) and control of high blood pressure have contributed significantly to these trends.

Original languageEnglish (US)
Pages (from-to)95-118
Number of pages24
JournalBiometrics
Volume38 Suppl
DOIs
StatePublished - Jan 1 1982

Fingerprint

Coronary Heart Disease
Cholesterol
Nutrition
Coronary Disease
cholesterol
dietary fat
hypertension
Diet
animal research
diet
Lipids
high sodium diet
Hypertension
Blood pressure
Blood Pressure
Fats
Oils and fats
very low density lipoprotein
hypercholesterolemia
smoking (food products)

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics

Cite this

Stamler, J. / Diet and coronary heart disease. In: Biometrics. 1982 ; Vol. 38 Suppl. pp. 95-118.
@article{c09d5b82c98b47ebb68a6fcdc3107e5e,
title = "Diet and coronary heart disease.",
abstract = "This paper reviews key aspects of the relationship of diet to coronary heart disease, as demonstrated in epidemiologic and other research over the last 25 or more years. It summarizes the extensive findings that have demonstrated an etiologically significant association among dietary lipid, serum cholesterol, and coronary heart disease; between caloric imbalance and two of the major CHD risk factors, hypertension and hypercholesterolemia; on the relationship between habitual diet high in sodium and hypertension. It also reviews the data on the relationship of habitual dietary lipid intake of individuals within a population to the serum cholesterol and CHD risk of individuals, indicating that valid positive findings in this area are consistent with evidence from cross-population epidemiologic studies, controlled experiments on diet change in man, and findings from animal research. It delineates the controlled experiments on diet change in man, and findings from animal research. It delineates the methodological problems that have stood in the way of the sound elucidation of this matter, and of the similar ones making it difficult to fully resolve the issue of the relationship of habitual dietary sodium intake of individuals within a population to their blood pressure. It reviews recent findings on the relationship of diet, particularly dietary lipid and calorie balance, to fractions of plasma total cholesterol, i.e., LDL-cholesterol, VLDL-cholesterol, and HDL-cholesterol, and summarizes the evidence indicating that recommendations for improved nutrition in the United States--emphasizing sizable reduction in saturated fat and cholesterol intake, moderate decrease in intake of total fat and of refined and processed sugars, and of calories for overweight persons--produce changes in plasma lipidlipoprotein levels that are favorable in all respects. Finally, it summarizes the findings with respect to the marked decline in mortality from coronary heart disease, stroke, all cardiovascular diseases, and all causes in the United States from 1968 to 1978, and presents evidence indicating that improvements in life style (eating, smoking, and exercise habits) and control of high blood pressure have contributed significantly to these trends.",
author = "J. Stamler",
year = "1982",
month = "1",
day = "1",
doi = "10.2307/2529859",
language = "English (US)",
volume = "38 Suppl",
pages = "95--118",
journal = "Biometrics",
issn = "0006-341X",
publisher = "Wiley-Blackwell",

}

Diet and coronary heart disease. / Stamler, J.

In: Biometrics, Vol. 38 Suppl, 01.01.1982, p. 95-118.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Diet and coronary heart disease.

AU - Stamler, J.

PY - 1982/1/1

Y1 - 1982/1/1

N2 - This paper reviews key aspects of the relationship of diet to coronary heart disease, as demonstrated in epidemiologic and other research over the last 25 or more years. It summarizes the extensive findings that have demonstrated an etiologically significant association among dietary lipid, serum cholesterol, and coronary heart disease; between caloric imbalance and two of the major CHD risk factors, hypertension and hypercholesterolemia; on the relationship between habitual diet high in sodium and hypertension. It also reviews the data on the relationship of habitual dietary lipid intake of individuals within a population to the serum cholesterol and CHD risk of individuals, indicating that valid positive findings in this area are consistent with evidence from cross-population epidemiologic studies, controlled experiments on diet change in man, and findings from animal research. It delineates the controlled experiments on diet change in man, and findings from animal research. It delineates the methodological problems that have stood in the way of the sound elucidation of this matter, and of the similar ones making it difficult to fully resolve the issue of the relationship of habitual dietary sodium intake of individuals within a population to their blood pressure. It reviews recent findings on the relationship of diet, particularly dietary lipid and calorie balance, to fractions of plasma total cholesterol, i.e., LDL-cholesterol, VLDL-cholesterol, and HDL-cholesterol, and summarizes the evidence indicating that recommendations for improved nutrition in the United States--emphasizing sizable reduction in saturated fat and cholesterol intake, moderate decrease in intake of total fat and of refined and processed sugars, and of calories for overweight persons--produce changes in plasma lipidlipoprotein levels that are favorable in all respects. Finally, it summarizes the findings with respect to the marked decline in mortality from coronary heart disease, stroke, all cardiovascular diseases, and all causes in the United States from 1968 to 1978, and presents evidence indicating that improvements in life style (eating, smoking, and exercise habits) and control of high blood pressure have contributed significantly to these trends.

AB - This paper reviews key aspects of the relationship of diet to coronary heart disease, as demonstrated in epidemiologic and other research over the last 25 or more years. It summarizes the extensive findings that have demonstrated an etiologically significant association among dietary lipid, serum cholesterol, and coronary heart disease; between caloric imbalance and two of the major CHD risk factors, hypertension and hypercholesterolemia; on the relationship between habitual diet high in sodium and hypertension. It also reviews the data on the relationship of habitual dietary lipid intake of individuals within a population to the serum cholesterol and CHD risk of individuals, indicating that valid positive findings in this area are consistent with evidence from cross-population epidemiologic studies, controlled experiments on diet change in man, and findings from animal research. It delineates the controlled experiments on diet change in man, and findings from animal research. It delineates the methodological problems that have stood in the way of the sound elucidation of this matter, and of the similar ones making it difficult to fully resolve the issue of the relationship of habitual dietary sodium intake of individuals within a population to their blood pressure. It reviews recent findings on the relationship of diet, particularly dietary lipid and calorie balance, to fractions of plasma total cholesterol, i.e., LDL-cholesterol, VLDL-cholesterol, and HDL-cholesterol, and summarizes the evidence indicating that recommendations for improved nutrition in the United States--emphasizing sizable reduction in saturated fat and cholesterol intake, moderate decrease in intake of total fat and of refined and processed sugars, and of calories for overweight persons--produce changes in plasma lipidlipoprotein levels that are favorable in all respects. Finally, it summarizes the findings with respect to the marked decline in mortality from coronary heart disease, stroke, all cardiovascular diseases, and all causes in the United States from 1968 to 1978, and presents evidence indicating that improvements in life style (eating, smoking, and exercise habits) and control of high blood pressure have contributed significantly to these trends.

UR - http://www.scopus.com/inward/record.url?scp=0020107033&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020107033&partnerID=8YFLogxK

U2 - 10.2307/2529859

DO - 10.2307/2529859

M3 - Review article

C2 - 7046825

AN - SCOPUS:0020107033

VL - 38 Suppl

SP - 95

EP - 118

JO - Biometrics

JF - Biometrics

SN - 0006-341X

ER -