Dietary cholesterol and incidence of lung cancer: The western electric study

Richard B. Shekelle; Arthur H. Rossof; Jeremiah Stamler

doi:10.1093/oxfordjournals.aje.a116119

Dietary cholesterol and incidence of lung cancer: The western electric study

Richard B. Shekelle^*, Arthur H. Rossof, Jeremiah Stamler

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

The hypothesis that dietary cholesterol is positively associated with lung cancer was investigated in a 24-year cohort study of 1,878 middle-aged men who were employed in 1958 by the Western Electric Company in Chicago. The relative risk of lung cancer associated with an increment in dietary cholesterol of 500 mg/day was 1.9 (95 percent confidence interval 1.1-3.4) after adjustment for cigarettes, age, and intake of beta-carotene and fat. Results suggested that the association was specific to cholesterol from eggs. Further research is needed to understand the basis for this association.

Original language	English (US)
Pages (from-to)	480-484
Number of pages	5
Journal	American journal of epidemiology
Volume	134
Issue number	5
DOIs	https://doi.org/10.1093/oxfordjournals.aje.a116119
State	Published - Sep 1 1991
Externally published	Yes

Keywords

Cholesterol
Diet
Lung neoplasms

ASJC Scopus subject areas

Epidemiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/oxfordjournals.aje.a116119

Cite this

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title = "Dietary cholesterol and incidence of lung cancer: The western electric study",

abstract = "The hypothesis that dietary cholesterol is positively associated with lung cancer was investigated in a 24-year cohort study of 1,878 middle-aged men who were employed in 1958 by the Western Electric Company in Chicago. The relative risk of lung cancer associated with an increment in dietary cholesterol of 500 mg/day was 1.9 (95 percent confidence interval 1.1-3.4) after adjustment for cigarettes, age, and intake of beta-carotene and fat. Results suggested that the association was specific to cholesterol from eggs. Further research is needed to understand the basis for this association.",

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AB - The hypothesis that dietary cholesterol is positively associated with lung cancer was investigated in a 24-year cohort study of 1,878 middle-aged men who were employed in 1958 by the Western Electric Company in Chicago. The relative risk of lung cancer associated with an increment in dietary cholesterol of 500 mg/day was 1.9 (95 percent confidence interval 1.1-3.4) after adjustment for cigarettes, age, and intake of beta-carotene and fat. Results suggested that the association was specific to cholesterol from eggs. Further research is needed to understand the basis for this association.

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KW - Lung neoplasms

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Dietary cholesterol and incidence of lung cancer: The western electric study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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