Dietary cholesterol and incidence of lung cancer: The western electric study

Richard B. Shekelle*, Arthur H. Rossof, Jeremiah Stamler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


The hypothesis that dietary cholesterol is positively associated with lung cancer was investigated in a 24-year cohort study of 1,878 middle-aged men who were employed in 1958 by the Western Electric Company in Chicago. The relative risk of lung cancer associated with an increment in dietary cholesterol of 500 mg/day was 1.9 (95 percent confidence interval 1.1-3.4) after adjustment for cigarettes, age, and intake of beta-carotene and fat. Results suggested that the association was specific to cholesterol from eggs. Further research is needed to understand the basis for this association.

Original languageEnglish (US)
Pages (from-to)480-484
Number of pages5
JournalAmerican journal of epidemiology
Issue number5
StatePublished - Sep 1 1991


  • Cholesterol
  • Diet
  • Lung neoplasms

ASJC Scopus subject areas

  • Epidemiology


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