TY - JOUR
T1 - Dietary intake and urinary excretion of selenium in the Japanese adult population
T2 - The INTERMAP Study Japan
AU - Yoneyama, S.
AU - Miura, K.
AU - Itai, K.
AU - Yoshita, K.
AU - Nakagawa, H.
AU - Shimmura, T.
AU - Okayama, A.
AU - Sakata, K.
AU - Saitoh, S.
AU - Ueshima, H.
AU - Elliott, P.
AU - Stamler, J.
N1 - Funding Information:
We acknowledge the fine collaborative efforts of all INTER-MAP staff. A comprehensive listing of colleagues from participating field centers, coordinating centers, Steering and Editorial, and Advisory Committees is given in a reference here (Stamler et al., 2003b). This study was partly supported by Grant-in-Aid for Scientific Research (A) (no. 090357003) and (C) (no. 13670394) from the Ministry of Education, Science, Sports and Culture, Japan, and by Grant 2-RO1-HL50490 from the US National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
PY - 2008
Y1 - 2008
N2 - Objective: This study is to examine the relationship between dietary selenium intake and 24-h urinary selenium excretion in Japanese population samples participating in the INTERMAP Study. Methods: Using highly standardized methods, we assessed individual dietary selenium intake from four 24-h dietary recalls and measured urinary selenium excretion in two timed 24-h urine collections in 1145 Japanese participants (574 men and 571 women) ages 40-59 years in four areas of Japan. Results: The medians of dietary selenium intake were 177.5 μg/day in men and 139.8 μg/day in women; the medians of 24-h urinary selenium excretion were 127.9 μg/day in men and 109.4 μg/day in women, that is, urinary excretion was estimated to be 73% of dietary intake in men and 77% in women. Dietary selenium intake was significantly correlated with 24-h urinary selenium excretion (r = 0.24 in men, r = 0.18 in women; P < 0.001). With dietary selenium intake and urinary selenium excretion expressed per kg of body weight, values were similar for men and women (dietary intake, 2.7 μg/kg body weight in men and 2.5 μg/kg body weight in women; urinary excretion, 2.0 μg/kg body weight in men and 2.0 μg/kg body weight in women). Conclusion: Dietary intake and 24-h urinary excretion of selenium are related in the Japanese adult population.
AB - Objective: This study is to examine the relationship between dietary selenium intake and 24-h urinary selenium excretion in Japanese population samples participating in the INTERMAP Study. Methods: Using highly standardized methods, we assessed individual dietary selenium intake from four 24-h dietary recalls and measured urinary selenium excretion in two timed 24-h urine collections in 1145 Japanese participants (574 men and 571 women) ages 40-59 years in four areas of Japan. Results: The medians of dietary selenium intake were 177.5 μg/day in men and 139.8 μg/day in women; the medians of 24-h urinary selenium excretion were 127.9 μg/day in men and 109.4 μg/day in women, that is, urinary excretion was estimated to be 73% of dietary intake in men and 77% in women. Dietary selenium intake was significantly correlated with 24-h urinary selenium excretion (r = 0.24 in men, r = 0.18 in women; P < 0.001). With dietary selenium intake and urinary selenium excretion expressed per kg of body weight, values were similar for men and women (dietary intake, 2.7 μg/kg body weight in men and 2.5 μg/kg body weight in women; urinary excretion, 2.0 μg/kg body weight in men and 2.0 μg/kg body weight in women). Conclusion: Dietary intake and 24-h urinary excretion of selenium are related in the Japanese adult population.
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U2 - 10.1038/sj.ejcn.1602842
DO - 10.1038/sj.ejcn.1602842
M3 - Article
C2 - 17622257
AN - SCOPUS:53649109817
SN - 0954-3007
VL - 62
SP - 1187
EP - 1193
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
IS - 10
ER -