Dietary Management of Eosinophilic Esophagitis

Bethany Doerfler, Angela Y. Lam, Nirmala Gonsalves*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Eosinophilic esophagitis (EoE) is a chronic immune-mediated food antigen–driven disease characterized by tissue eosinophilia and clinical symptoms of esophageal dysfunction. Medical and dietary therapies can be offered as treatment options in both pediatric and adult populations. Advances in nutritional research in EoE have produced different levels of dietary restriction, ranging from elimination of a single food group to more extensive restriction such as the two-food elimination diet, four-food elimination diet, or six-food elimination diet. Efficacy and outcomes vary for each level of restriction. The option of using dietary therapy allows clinicians to partner with patients in shared decision-making to balance the right level of food antigen restriction for the desired outcome. Key considerations when choosing dietary therapy hinge on patient preference and resources, food-related quality of life, and the ability to provide nutritional diversity and maintain nutritional parameters. This article highlights these considerations and offers clinical pearls to guide clinicians who wish to incorporate dietary therapy of EoE into their practice.

Original languageEnglish (US)
Pages (from-to)680-690
Number of pages11
JournalGastroenterology and Hepatology
Issue number11
StatePublished - Nov 2023


  • dietary therapy
  • dysphagia
  • Eosinophilic esophagitis
  • food allergy
  • six-food elimination diet

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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