Dietary treatment of eosinophilic esophagitis in children

Amir F. Kagalwalla*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus that, in a genetically susceptible host, is triggered by a food antigen. Emerging evidence supports impaired epithelia barrier function as the key initial event in the development of EoE and other allergic diseases. Symptom resolution, histologic remission, and prevention of both disease and treatment-related complications are the goals of treatment. Successful dietary treatments include elemental and elimination diets, both empiric and allergy test directed. These treatments are dietary approaches to inducing clinical and histologic remission. Dietary therapy with an exclusive elemental diet offers the best response with a remission rate of more than 96%. Empiric elimination diets and allergy-directed diets offer similar response with remission induced in 3 of 4 subjects (75%). Cow's milk, wheat, egg and soy are the four common food antigens most likely to induce esophageal inflammation.

Original languageEnglish (US)
Pages (from-to)114-119
Number of pages6
JournalDigestive Diseases
Volume32
Issue number1-2
DOIs
StatePublished - Mar 2014

Keywords

  • Elemental diet
  • Patch testing
  • Six-food elimination diet

ASJC Scopus subject areas

  • Gastroenterology

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