Diets to prevent coronary heart disease 1957-2013: What have we learned?

James E. Dalen*, Stephen Devries

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

74 Scopus citations


Our understanding of the potential cardioprotective properties of nutrition is relatively recent, with most relevant studies completed in the last several decades. During that time, there has been an evolution in the focus of nutritional intervention. Early trials emphasized reduction of dietary fat with the goal of preventing heart disease by reducing serum cholesterol. Results from trials focused exclusively on dietary fat reduction were disappointing, prompting subsequent studies incorporating a whole diet approach with a nuanced recommendation for fat intake. The Mediterranean-style diet, with a focus on vegetables, fruit, fish, whole grains, and olive oil, has proven to reduce cardiovascular events to a degree greater than low-fat diets and equal to or greater than the benefit observed in statin trials.

Original languageEnglish (US)
Pages (from-to)364-369
Number of pages6
JournalAmerican journal of medicine
Issue number5
StatePublished - May 2014


  • CHD prevention
  • Keywords
  • Low-fat diets
  • Mediterranean diet
  • Reducing cholesterol

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Diets to prevent coronary heart disease 1957-2013: What have we learned?'. Together they form a unique fingerprint.

Cite this