Diffuse Uveal Melanocytic Proliferation with Primary Vitreoretinal Lymphoma

Ilya Leskov, Alice T. Lyon, Lee M. Jampol*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Importance: Bilateral diffuse uveal melanocytic proliferation is a rare sign of several systemic malignant neoplasms. Observations: A patient presenting with uveal melanocytic proliferation underwent a detailed physical examination and extensive imaging. No systemic malignant neoplasm was found. Chorioretinal biopsy was performed, and its immunohistochemical results revealed the presence of primary vitreoretinal lymphoma. Conclusions and Relevance: This patient's results suggest that diffuse uveal melanocytic proliferation may be associated not just with systemic malignant disease, but also with primary intraocular tumors, in this case a primary vitreoretinal lymphoma.

Original languageEnglish (US)
Pages (from-to)834-837
Number of pages4
JournalJAMA ophthalmology
Issue number7
StatePublished - Jul 2019

ASJC Scopus subject areas

  • Ophthalmology


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