Digoxin

Eric J. Eichhorn, Mihai Gheorghiade*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

116 Scopus citations

Abstract

After 200 years of use, digitalis still appears to have a place in our armamentarium for heart failure and atrial fibrillation despite the proven survival benefits with ACE inhibitors and β-blockers. Digoxin therapy is inexpensive and well tolerated and may result in considerable savings. Digoxin is the only oral inotrope that does not increase mortality in heart failure patients, particularly if low doses are being used. Digoxin therapy should be used in patients with systolic heart failure who continue to have signs and symptoms despite therapeutic doses of ACE inhibitors or diuretics or in patients with atrial fibrillation with or without heart failure for rate control.

Original languageEnglish (US)
Pages (from-to)251-266
Number of pages16
JournalProgress in Cardiovascular Diseases
Volume44
Issue number4
DOIs
StatePublished - 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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