@inproceedings{60a1618822c743638d59624054fc9f9f,
title = "Direct delivery and submicron patterning of DNA by nanofountain probe",
abstract = "We present biomolecular patterning results using a nanofountain probe (NFP) that permits microfluidic direct delivery of oligonucleotides without hydrophilic modification of the tip for coating effectiveness. This is advantageous for integrated probes arrays that may require different functionalization to support writing with different inks, and in which damage of tips is more likely and critical. A linear array of NFPs was used to produce DNA nanoarrays. Routine feature sizes in the submicron range were obtained to prove both microfluidic transport and high-resolution writing. Gold nanoparticles functionalized with complementary sequence were hybridized to the patterned oligonucleotides, to demonstrate the biological activity of the deposited features. The results demonstrated the potential of our device as a production tool for nanofabrication of biomolecular arrays.",
author = "Kim, {Keun Ho} and Raymond Sanedrin and Lee, {Seung W.} and Nicolaie Moldovan and Mirkin, {Chad A.} and Espinosa, {Horacio D.}",
year = "2007",
language = "English (US)",
isbn = "1604232226",
series = "Proceedings of the SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2007",
pages = "250--259",
booktitle = "Proceedings of the SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2007",
note = "SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2007 ; Conference date: 03-06-2007 Through 06-06-2007",
}