Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood

Keyphrases

• K-ATPase 100%
• Alternating Hemiplegia of childhood 100%
• Pump Function 100%
• Induced Pluripotent Stem Cells (iPSCs) 40%
• ATP1A3 Gene 20%
• Membrane Potential 20%
• Action Potential Firing 20%
• Firing Frequency 20%
• Potential Impact 10%
• Neurological Diseases 10%
• Fibroblasts 10%
• Neuronal Excitability 10%
• Neurological Phenotype 10%
• Glial Cells 10%
• Genetic Defects 10%
• Human Induced Pluripotent Stem Cell-derived Neurons 10%
• Resting Membrane Potential 10%
• Whole-cell Currents 10%
• Current Clamp 10%
• Voltage-gated Sodium Channel 10%
• Outward Current 10%
• Cellular Models 10%
• Cortical Excitatory Neuron 10%
• Electrophysiological Properties 10%
• ATP1A3 10%
• Pump Current 10%
• Cellular Excitability 10%
• Catalytic Subunit 10%
• Human Neurons 10%
• Potassium 10%
• Ion Transport 10%
• Neuronal Differentiation 10%
• Functional Disturbances 10%
• Mammalian Neurons 10%
• Neurodevelopmental Syndrome 10%
• Equilibrium Potential 10%
• Resting Potential 10%
• Transport Activity 10%
• Ouabain 10%
• Low Voltage 10%
• Channel Availability 10%
• Neurogenin2 10%
• Current Pump 10%

Neuroscience

• Hemiplegia 100%
• Adenosine Triphosphatase (Potassium Sodium) 100%
• Stem Cell 50%
• Membrane Potential 20%
• Resting Potential 20%
• Evoked Potential 20%
• Neuronal Excitability 10%
• Nervous System Disorder 10%
• Excitability 10%
• Nerve Cell Differentiation 10%
• Voltage Gated Sodium Channel 10%
• Enzyme Active Site 10%
• Ion Transport 10%
• Ouabain 10%
• Neurogenin 2 10%
• Microglia 10%
• Fibroblast 10%