Direct observation of the hole carriers in DNA photoinduced charge transport

Michelle A. Harris, Ashutosh Kumar Mishra, Ryan M. Young, Kristen E. Brown, Michael R. Wasielewski, Frederick D. Lewis*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


The excited state behavior of DNA hairpins possessing a diphenylacetylenedicarboxamide (DPA) linker separated from a single guanine-cytosine (G-C) base pair by zero-to-six adenine-thymine (A-T) base pairs has been investigated. In the case of hairpins with zero or one A-T separating DPA and G, formation of both DPA anion radical (DPA) and G cation radical (G) are directly observed and characterized by their transient absorption and stimulated Raman spectra. For hairpins with two or more intervening A-T, the transient absorption spectra of DPA) and the adenine polaron (An) are observed. In addition to characterization of the hole carriers, the dynamics of each step in the charge separation and charge recombination process as well as the overall efficiency of charge separation have been determined, thus providing a complete account of the mechanism and dynamics of photoinduced charge transport in these DNA hairpins.

Original languageEnglish (US)
Pages (from-to)5491-5494
Number of pages4
JournalJournal of the American Chemical Society
Issue number17
StatePublished - May 4 2016

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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