Discourse production following injury to the dorsolateral prefrontal cortex

Carl Coelho*, Karen Lĉ, Jennifer Mozeiko, Frank Krueger, Jordan Henry Grafman

*Corresponding author for this work

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Individuals with damage to the prefrontal cortex, and the dorsolateral prefrontal cortex (DLPFC) in particular, often demonstrate difficulties with the formulation of complex language not attributable to aphasia. The present study employed a discourse analysis procedure to characterize the language of individuals with left (L) or right (R) DLPFC lesions. All participants were 30-35 years post-onset of injury and presented with persistent discourse impairments. The discourse performance of the R DLPFC group was not significantly different from either the L DLPFC group or the non-injured comparison group. Individuals from the L DLPFC group demonstrated specific difficulties with narrative coherence and inclusion of critical story components. Both measures were significantly different from the comparison group. The discourse ability of the DLPFC groups was significantly correlated with measures of working memory. Findings support the use of discourse analysis for examining language impairments in individuals with PFC lesions.

Original languageEnglish (US)
Pages (from-to)3564-3572
Number of pages9
JournalNeuropsychologia
Volume50
Issue number14
DOIs
StatePublished - Dec 1 2012

Keywords

  • Discourse analysis
  • Discourse production
  • Dorsolateral prefrontal cortex
  • Language production
  • Working memory

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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