TY - JOUR
T1 - DISEASE, LIFESTYLE, AND CONSANGUINITY IN 58 AMERICAN GYPSIES
AU - Thomas, JamesD
AU - Doucette, MargaretM
AU - Catanzano Thomas, Donna
AU - Stoeckle, JohnD
PY - 1987/8/15
Y1 - 1987/8/15
N2 - Medical data on 58 Gypsies in the area of Boston, Massachusetts, were analysed together with a pedigree linking 39 of them in a large extended kindred. Hypertension was found in 73%, diabetes in 46%, hypertriglyceridaemia in 80%, hypercholesterolaemia in 67%, occlusive vascular disease in 39%, and chronic renal insufficiency in 20%. 86% smoked cigarettes and 84% were obese. Thirteen of twenty-one marriages were consanguineous, yielding an inbreeding coefficient of 0·017. The analysis suggests that both heredity and environment influence the striking pattern of vascular disease in American Gypsies.
AB - Medical data on 58 Gypsies in the area of Boston, Massachusetts, were analysed together with a pedigree linking 39 of them in a large extended kindred. Hypertension was found in 73%, diabetes in 46%, hypertriglyceridaemia in 80%, hypercholesterolaemia in 67%, occlusive vascular disease in 39%, and chronic renal insufficiency in 20%. 86% smoked cigarettes and 84% were obese. Thirteen of twenty-one marriages were consanguineous, yielding an inbreeding coefficient of 0·017. The analysis suggests that both heredity and environment influence the striking pattern of vascular disease in American Gypsies.
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U2 - 10.1016/S0140-6736(87)92392-0
DO - 10.1016/S0140-6736(87)92392-0
M3 - Article
C2 - 2886831
AN - SCOPUS:0023274511
SN - 0140-6736
VL - 330
SP - 377
EP - 379
JO - The Lancet
JF - The Lancet
IS - 8555
ER -
