Dispersion of refractoriness and unidirectional block in a model of ischemic myocardium

N. Maglaveras*, F. J L van Capelle, M. Allessie, A. V. Sahakian, C. Pappas, M. Strintzis

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ischemia effects on propagation characteristics are studied in a one-dimensional model of myocardium using the Luo-Rudy model. In particular the effects of changes in electrophysiologic parameters on propagation block, action potential duration (APD) and the effects of premature impulses in propagation characteristics around the border zone between normal and ischemic tissue are studied. It is shown that the direction of propagation coupled with changes in coupling resistance and resting membrane potential plays a dramatic role in altering propagation characteristics and action potential duration spatial distribution.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
PublisherPubl by IEEE
Pages663-666
Number of pages4
ISBN (Print)0818654708
StatePublished - Dec 1 1993
EventProceedings of the 1993 Conference on Computers in Cardiology - London, UK
Duration: Sep 5 1993Sep 8 1993

Publication series

NameComputers in Cardiology
ISSN (Print)0276-6574

Other

OtherProceedings of the 1993 Conference on Computers in Cardiology
CityLondon, UK
Period9/5/939/8/93

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ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

Cite this

Maglaveras, N., van Capelle, F. J. L., Allessie, M., Sahakian, A. V., Pappas, C., & Strintzis, M. (1993). Dispersion of refractoriness and unidirectional block in a model of ischemic myocardium. In Computers in Cardiology (pp. 663-666). (Computers in Cardiology). Publ by IEEE.