Disruption of the p53-Mdm2 complex by nutlin-3 reveals different cancer cell phenotypes

Medicine and Dentistry

• Phenotype 100%
• Cancer Cell 100%
• Protein P53 100%
• Mdm2 100%
• Nutlin 3 100%
• Cells 30%
• DNA Damage 20%
• Single Nucleotide Polymorphism 5%
• Complementary DNA 5%
• Programmed Cell Death 5%
• Malignant Neoplasm 5%
• Estrogen 5%
• Exon 5%
• Genotype 5%
• Transactivation 5%
• Chemotherapeutic Agent 5%
• Chromatin 5%
• MCF-7 5%
• Drug 5%
• Etoposide 5%
• Cancer Cell Line 5%
• DNA Damage Response 5%
• Gene Splicing 5%
• Treatment Development 5%
• Position 5%

Biochemistry, Genetics and Molecular Biology

• Phenotype 100%
• Cancer Cell 100%
• P53 100%
• Mdm2 100%
• Nutlin 100%
• DNA Damage 20%
• Wild Type 5%
• Development 5%
• Apoptosis 5%
• Classification 5%
• Molecular Cloning 5%
• Genotyping 5%
• Isoform 5%
• Transactivation 5%
• Chromatin 5%
• Single-Nucleotide Polymorphism 5%
• RNA Splicing 5%
• DNA Damage Response 5%
• Sequencing 5%
• Position 5%

INIS

• cancer 100%
• phenotype 100%
• dna damages 100%
• humans 40%
• drugs 20%
• comparative evaluations 20%
• genes 20%
• nucleotides 20%
• amplification 20%
• chromatin 20%
• apoptosis 20%
• splicing 20%
• estrogens 20%
• genotype 20%
• exons 20%
• cloning 20%