Disseminated aspergillosis in a patient with cystic fibrosis and allergic bronchopulmonary aspergillosis

Youngran Chung*, Jerome R. Kraut, Arvey M. Stone, Jonas Valaitis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is a, well‐known complication of cysticfibrosis (CF), with an estimated incidence of up to 11%. In patients with CF, the diagnosis of ABPA must be based on significant elevation of Aspergillus fumigatus (Af) antibody and total serum IgE, since it is common to already have other clinical and laboratory features of ABPA (Laufer et al., J Allergy Clin Immunol. 1984; 73:44–48). Once ABPA is identified in a patient, institution of corticosteroids is standard therapy. Invasive aspergillosis is a rare occurrence in patients with CF with or without ABPA, and has been reported in only one young adult who did not have ABPA (Giudotti et al., Am J Med Sci. 1982; 283:157–160). We present a case of a 15‐year‐old male with CF and ABPA who developed disseminated aspergillosis. Pediatr Pulmonol. 1994; 17:131–134. © 1994 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)131-134
Number of pages4
JournalPediatric Pulmonology
Volume17
Issue number2
DOIs
StatePublished - Feb 1994

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

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