Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris

Simon S. Yoo*, Mark Tran, Grant Anhalt, Terry Barrett, Eric C. Vonderheid

*Corresponding author for this work

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Cryptococcal infections are seen mainly in immunocompromised hosts. The cutaneous manifestations of infection can include papules, plaques, nodules, vesicles, ulcers, ecchymosis, and, rarely, cellulitis. Cryptococcal meningitis is a life-threatening complication of this disease. Pemphigus vulgaris is a rare auto-immune blistering disease that can also be life-threatening. Treatment of pemphigus commonly entails both corticosteroids and steroid-sparing agents. We present a case of disseminated cryptococcal infection in a patient with pemphigus vulgaris treated with high dose corticosteroids as monotherapy. This case provides an opportunity to discuss the difficulty of managing two potentially mortal conditions in which the treatment of pemphigus vulgaris may exacerbate the disseminated cryptococcal infection.

Original languageEnglish (US)
Pages (from-to)405-410
Number of pages6
JournalJournal of Dermatology
Volume30
Issue number5
DOIs
StatePublished - May 1 2003

Fingerprint

Cryptococcosis
Pemphigus
Prednisone
Infection
Adrenal Cortex Hormones
Cryptococcal Meningitis
Ecchymosis
Skin Manifestations
Cellulitis
Immune System Diseases
Immunocompromised Host
Ulcer
Steroids
Therapeutics

Keywords

  • Cellulitis
  • Corticosteroids
  • Cryptococcus
  • Pemphigus vulgaris

ASJC Scopus subject areas

  • Dermatology

Cite this

Yoo, Simon S. ; Tran, Mark ; Anhalt, Grant ; Barrett, Terry ; Vonderheid, Eric C. / Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris. In: Journal of Dermatology. 2003 ; Vol. 30, No. 5. pp. 405-410.
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Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris. / Yoo, Simon S.; Tran, Mark; Anhalt, Grant; Barrett, Terry; Vonderheid, Eric C.

In: Journal of Dermatology, Vol. 30, No. 5, 01.05.2003, p. 405-410.

Research output: Contribution to journalArticle

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AB - Cryptococcal infections are seen mainly in immunocompromised hosts. The cutaneous manifestations of infection can include papules, plaques, nodules, vesicles, ulcers, ecchymosis, and, rarely, cellulitis. Cryptococcal meningitis is a life-threatening complication of this disease. Pemphigus vulgaris is a rare auto-immune blistering disease that can also be life-threatening. Treatment of pemphigus commonly entails both corticosteroids and steroid-sparing agents. We present a case of disseminated cryptococcal infection in a patient with pemphigus vulgaris treated with high dose corticosteroids as monotherapy. This case provides an opportunity to discuss the difficulty of managing two potentially mortal conditions in which the treatment of pemphigus vulgaris may exacerbate the disseminated cryptococcal infection.

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