Disseminated Herpes Simplex Infection with Retinitis In A Renal Allograft Recipient

E. Uninsky, L. M. Jampol*, S. Kaufman, S. Naraqi

*Corresponding author for this work

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

An immunosuppressed recipient of a renal allograft developed bilateral necrotizing retinitis. Disseminated herpes simplex infection was documented by clinical findings and serologic and viral culture studies. Cultures and serologic tests for cytomegalovirus were negative. The evidence strongly favored the diagnosis of herpes simplex retinitis. Tapering of immunosuppressive drugs and administration of adenine arabinoside appeared to halt temporarily the progression of the disease in one eye and resulted in healing of the retinitis in the other eye. Subsequent progression of the more severely involved right eye resulted in an exudative retinal detachment and loss of vision prior to the patient's death from meningoencephalitis. Herpes simplex retinitis must be considered in the differential diagnosis of necrotizing retinitis in an immunosuppressed patient.

Original languageEnglish (US)
Pages (from-to)175-178
Number of pages4
JournalOphthalmology
Volume90
Issue number2
DOIs
StatePublished - 1983

Keywords

  • adenine arabinoside
  • cytomegalovirus
  • herpes simplex
  • renal transplant
  • retinitis

ASJC Scopus subject areas

  • Ophthalmology

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