Disseminated intravascular coagulation after excision of giant hemangioma

Juda Z. Jona, Hau C. Kwaan*, Marija Bjelan, John G. Raffensperger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


The importance of recognizing disseminated intravascular coagulation as the cause of severe bleeding diathesis in a patient with giant hemangioma is illustrated. A sixteen year old boy with multiple giant cavernous hemangiomas had massive local bleeding after each of the three times surgical excision of the hemangiomas was carried out. Detailed laboratory studies performed on the third occasion provided evidence of disseminated intravascular coagulation as shown by the decreased platelet counts and plasma levels of fibrinogen and factors V and VIII, the prolongation of prothrombin time, partial thromboplastin time, thrombin time, and arvin time, the presence of fibrinogen degradation products, and the increased fibrinolytic activity. Cessation of bleeding accompanied by a return of the laboratory values to within normal limits occurred after correction of the disseminated intravascular coagulation with heparin and acetylsalicylic acid. The use of epsilon aminocaproic acid is contraindicated in this situation.

Original languageEnglish (US)
Pages (from-to)588-592
Number of pages5
JournalThe American Journal of Surgery
Issue number5
StatePublished - May 1974

ASJC Scopus subject areas

  • Surgery


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