TY - JOUR
T1 - Dissemination of strongyloides stercoralis in a patient with systemic lupus erythematosus after initiation of albendazole
T2 - A case report
AU - Hunter, Catherine J.
AU - Petrosyan, Mikael
AU - Asch, Morris
PY - 2008/5/14
Y1 - 2008/5/14
N2 - Introduction: Strongyloides stercoralis infection affects hundreds of millions of people worldwide. As immigration rates and international travel increase, so does the number of cases of strongyloidiasis in the United States. Although described both in immigrant and in immunosuppressed populations, hyperinfection and dissemination of S. stercoralis following the initiation of antiparasitic medication is a previously unreported phenomenon. Case presentation: Here we describe the case of a 38-year-old immunocompromised woman with systemic lupus erythematosus, who developed disseminated disease following treatment with albendazole (400 mg every 12 hours). Notably the patient was receiving oral prednisone (10 mg once daily), azathioprine (50 mg twice daily), and hydroxychloroquine (400 mg daily) at the time of hospitalization. The patient was subsequently treated successfully with ivermectin (200 mcg/kg daily). Conclusion: The reader should be aware that dissemination of S. stercoralis can occur even after the initiation of antiparasitic medication.
AB - Introduction: Strongyloides stercoralis infection affects hundreds of millions of people worldwide. As immigration rates and international travel increase, so does the number of cases of strongyloidiasis in the United States. Although described both in immigrant and in immunosuppressed populations, hyperinfection and dissemination of S. stercoralis following the initiation of antiparasitic medication is a previously unreported phenomenon. Case presentation: Here we describe the case of a 38-year-old immunocompromised woman with systemic lupus erythematosus, who developed disseminated disease following treatment with albendazole (400 mg every 12 hours). Notably the patient was receiving oral prednisone (10 mg once daily), azathioprine (50 mg twice daily), and hydroxychloroquine (400 mg daily) at the time of hospitalization. The patient was subsequently treated successfully with ivermectin (200 mcg/kg daily). Conclusion: The reader should be aware that dissemination of S. stercoralis can occur even after the initiation of antiparasitic medication.
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U2 - 10.1186/1752-1947-2-156
DO - 10.1186/1752-1947-2-156
M3 - Article
C2 - 18479527
AN - SCOPUS:45749100968
SN - 1752-1947
VL - 2
JO - Journal of Medical Case Reports
JF - Journal of Medical Case Reports
M1 - 156
ER -