Distribution excretion and metabolism of trifluoperazine methiodide-C14 in rats

C. L. Huang*, J. Z. Yeh

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The majority of the intraperitoneally administered trifluoperazine methiodide-C14 was excreted in feces by rats. No radioactivity was detected in the expired air of the animals. Blood level was generally low but detectable with a peak level at 1 hr; however the brain level was insignificant against the background at all times. Antimicrobial activities have been demonstrated. Metabolic studies indicated that the majority of this compound was excreted unchanged.

Original languageEnglish (US)
Pages (from-to)235-242
Number of pages8
JournalNeuropharmacology
Volume9
Issue number3
DOIs
StatePublished - May 1970

ASJC Scopus subject areas

  • Pharmacology
  • Cellular and Molecular Neuroscience

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