Diurnal rhythms in nociceptive thresholds of rats

J. Peter Rosenfeld*, Peter E. Rice

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


Paw lick, tail flick, and other nociceptive reaction latencies were observed in rats to be longer in the evening than in the daytime, suggesting an endogenous opiate mediated decrease in pain sensitivity in the evening in comparison with the daytime.

Original languageEnglish (US)
Pages (from-to)419-420
Number of pages2
JournalPhysiology and Behavior
Issue number2
StatePublished - Aug 1979


  • Diurnal
  • Endorphin
  • Enkephalin
  • Naloxone
  • Nociception
  • Pain

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience


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