Lanthanide metallocenes catalyze the regiospecific intermolecular addition of primary amines to acetylenic, olefinic, and diene substrates at rates which are ∼1/1000 those of the most rapid intramolecular analogues. Kinetic and mechanistic data argue for turnover-limiting C≡C/C=C insertion into a Ln-N bond, followed by protonolysis of the resulting Ln-C bond.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry