DNA-array based transcriptional analysis elucidates granulocytic differentiation of human stem cells

L. T. Huang*, William M Miller, E. T. Papoutsakis

*Corresponding author for this work

Research output: Contribution to conferencePaper

Abstract

The DNA-array based transcriptional analysis helped to elucidate granulocytic differentiation of human stem cells. The initiation and continuation of granulopoieses consists of a delicate balance of the three processes of expansion, differentiation and apoptosis. The morphological and phenotypical changes associated with each process have provided clues to their underlying transcriptional program. The signaling pathway involves the interactions between and regulation of the three processes. DNA-microarray technology provides a detailed view of global gene expressions.

Original languageEnglish (US)
Number of pages1
StatePublished - Dec 1 2004
Event2004 AIChE Annual Meeting - Austin, TX, United States
Duration: Nov 7 2004Nov 12 2004

Other

Other2004 AIChE Annual Meeting
CountryUnited States
CityAustin, TX
Period11/7/0411/12/04

ASJC Scopus subject areas

  • Engineering(all)

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    Huang, L. T., Miller, W. M., & Papoutsakis, E. T. (2004). DNA-array based transcriptional analysis elucidates granulocytic differentiation of human stem cells. Paper presented at 2004 AIChE Annual Meeting, Austin, TX, United States.