TY - JOUR
T1 - DNA on stage
T2 - Showcasing oligonucleotides at surfaces and interfaces with second harmonic and vibrational sum frequency generation
AU - Walter, Stephanie R.
AU - Geiger, Franz M.
PY - 2010/1/1
Y1 - 2010/1/1
N2 - The field of nonlinear optics continues to expand and surprise. The ability to study DNA with nonlinear optics has opened the door to understand, on a molecular level and without the use of external labels, the physical and chemical properties of DNA single and double strands at surfaces and interfaces. In this Perspective, we survey how nonlinear optical probes access the electronic, vibrational, electrostatic, and chiral signatures of interfacial DNA in its native state. We also show how this exciting new field is directly applicable to tracking and understanding molecular recognition in DNA oligonucleotides and aptamers.
AB - The field of nonlinear optics continues to expand and surprise. The ability to study DNA with nonlinear optics has opened the door to understand, on a molecular level and without the use of external labels, the physical and chemical properties of DNA single and double strands at surfaces and interfaces. In this Perspective, we survey how nonlinear optical probes access the electronic, vibrational, electrostatic, and chiral signatures of interfacial DNA in its native state. We also show how this exciting new field is directly applicable to tracking and understanding molecular recognition in DNA oligonucleotides and aptamers.
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U2 - 10.1021/jz9001086
DO - 10.1021/jz9001086
M3 - Article
AN - SCOPUS:77149157269
VL - 1
SP - 9
EP - 15
JO - Journal of Physical Chemistry Letters
JF - Journal of Physical Chemistry Letters
SN - 1948-7185
IS - 1
ER -