DNA self-assembly for constructing 3D boxes (Extended Abstract)

Ming-Yang Kao*, Vijay Ramachandran

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

16 Scopus citations


We propose a mathematical model of DNA self-assembly using 2D tiles to form 3D nanostructures. This is the first work to combine studies in self-assembly and nanotechnology in 3D, just as Rothemund and Winfree did in the 2D case. Our model is a more precise superset of their Tile Assembly Model that facilitates building scalable 3D molecules. Under our model, we present algorithms to build a hollow cube, which is intuitively one of the simplest 3D structures to construct. We also introduce five basic measures of complexity to analyze these algorithms. Our model and algorithmic techniques are applicable to more complex 2D and 3D nanostructures.

Original languageEnglish (US)
Title of host publicationAlgorithms and Computation - 12th International Symposium, ISAAC 2001, Proceedings
Number of pages13
StatePublished - 2001
Event12th International Symposium on Algorithms and Computation, ISAAC 2001 - Christchurch, New Zealand
Duration: Dec 19 2001Dec 21 2001

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume2223 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Other12th International Symposium on Algorithms and Computation, ISAAC 2001
Country/TerritoryNew Zealand

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science


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