3H-thymidine autoradiography showed an enhanced DNA synthesis, in acinar and islet cells of pancreas after partial hepatectomy in syrian golden hamsters. A significant nuclear labeling index of acinar cells was observed between 48 and 84 h and reached control levels by 120 h. An increased labeling index of islet cells was also observed, however, this increase was not statistically significant. These results indicate growth factor(s) produced after partial hepatectomy is capable of inducing DNA synthesis in pancreas.
- DNA synthesis
- Partial hepatectomy
- acinar cells
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)