DNA synthesis in exocrine and endocrine pancreas after partial hepatectomy in Syrian golden hamsters

M. S. Rao; V. Subbarao

doi:10.1007/BF01941543

DNA synthesis in exocrine and endocrine pancreas after partial hepatectomy in Syrian golden hamsters

M. S. Rao^*, V. Subbarao

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

³H-thymidine autoradiography showed an enhanced DNA synthesis, in acinar and islet cells of pancreas after partial hepatectomy in syrian golden hamsters. A significant nuclear labeling index of acinar cells was observed between 48 and 84 h and reached control levels by 120 h. An increased labeling index of islet cells was also observed, however, this increase was not statistically significant. These results indicate growth factor(s) produced after partial hepatectomy is capable of inducing DNA synthesis in pancreas.

Original language	English (US)
Pages (from-to)	833-834
Number of pages	2
Journal	Experientia
Volume	42
Issue number	7
DOIs	https://doi.org/10.1007/BF01941543
State	Published - Jul 1986

Keywords

DNA synthesis
Partial hepatectomy
acinar cells
thymidine

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1007/BF01941543

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abstract = "3H-thymidine autoradiography showed an enhanced DNA synthesis, in acinar and islet cells of pancreas after partial hepatectomy in syrian golden hamsters. A significant nuclear labeling index of acinar cells was observed between 48 and 84 h and reached control levels by 120 h. An increased labeling index of islet cells was also observed, however, this increase was not statistically significant. These results indicate growth factor(s) produced after partial hepatectomy is capable of inducing DNA synthesis in pancreas.",

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AU - Subbarao, V.

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N2 - 3H-thymidine autoradiography showed an enhanced DNA synthesis, in acinar and islet cells of pancreas after partial hepatectomy in syrian golden hamsters. A significant nuclear labeling index of acinar cells was observed between 48 and 84 h and reached control levels by 120 h. An increased labeling index of islet cells was also observed, however, this increase was not statistically significant. These results indicate growth factor(s) produced after partial hepatectomy is capable of inducing DNA synthesis in pancreas.

AB - 3H-thymidine autoradiography showed an enhanced DNA synthesis, in acinar and islet cells of pancreas after partial hepatectomy in syrian golden hamsters. A significant nuclear labeling index of acinar cells was observed between 48 and 84 h and reached control levels by 120 h. An increased labeling index of islet cells was also observed, however, this increase was not statistically significant. These results indicate growth factor(s) produced after partial hepatectomy is capable of inducing DNA synthesis in pancreas.

KW - DNA synthesis

KW - Partial hepatectomy

KW - acinar cells

KW - thymidine

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DNA synthesis in exocrine and endocrine pancreas after partial hepatectomy in Syrian golden hamsters

Abstract

Keywords

ASJC Scopus subject areas

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