Abstract
Children with myelodysplasia have an increased incidence of latex allergy, which can lead to severe intraoperative allergic reactions. Despite widespread recommendations to avoid intraoperative latex exposure, little evidence exists to support the efficacy of this practice. We examined the incidence of intraoperative allergic reactions in children with myelodysplasia who underwent 1,025 operations in a 36-month period before and after institution of a standardized latex-avoidance protocol. Risk factors for all intraoperative reaction were found to be a history of latex allergy (p = 0.001) and surgery performed before institution of the latex-avoidance protocol (p = 0.01). The estimate of increased risk for allergic reaction was 3.09 times higher in cases performed without latex avoidance. Recognized violation of the protocol after its institution led to severe allergic reactions in three patients. Our experience suggests that a latex avoidance protocol reduces intraoperative allergic reactions in children with myelodysplasia. Development of severe allergic reactions with violation of the protocol reinforces the importance of vigilance on the part of all operating room personnel in its implementation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 799-802 |
| Number of pages | 4 |
| Journal | Journal of Pediatric Orthopaedics |
| Volume | 16 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jan 1 1996 |
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Keywords
- Latex allergy
- Myelodysplasia
- Pediatric anesthesia
- Spina bifida
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Orthopedics and Sports Medicine
Cite this
}
Do latex precautions in children with myelodysplasia reduce intraoperative allergic reactions? / Birmingham, Patrick K; Dsida, Richard; Grayhack, John J; Han, Jianping; Wheeler, Melissa; Pongracic, Jacqueline A; Coté, Charles J.; Hall, Steven C.
In: Journal of Pediatric Orthopaedics, Vol. 16, No. 6, 01.01.1996, p. 799-802.Research output: Contribution to journal › Article
TY - JOUR
T1 - Do latex precautions in children with myelodysplasia reduce intraoperative allergic reactions?
AU - Birmingham, Patrick K
AU - Dsida, Richard
AU - Grayhack, John J
AU - Han, Jianping
AU - Wheeler, Melissa
AU - Pongracic, Jacqueline A
AU - Coté, Charles J.
AU - Hall, Steven C
PY - 1996/1/1
Y1 - 1996/1/1
N2 - Children with myelodysplasia have an increased incidence of latex allergy, which can lead to severe intraoperative allergic reactions. Despite widespread recommendations to avoid intraoperative latex exposure, little evidence exists to support the efficacy of this practice. We examined the incidence of intraoperative allergic reactions in children with myelodysplasia who underwent 1,025 operations in a 36-month period before and after institution of a standardized latex-avoidance protocol. Risk factors for all intraoperative reaction were found to be a history of latex allergy (p = 0.001) and surgery performed before institution of the latex-avoidance protocol (p = 0.01). The estimate of increased risk for allergic reaction was 3.09 times higher in cases performed without latex avoidance. Recognized violation of the protocol after its institution led to severe allergic reactions in three patients. Our experience suggests that a latex avoidance protocol reduces intraoperative allergic reactions in children with myelodysplasia. Development of severe allergic reactions with violation of the protocol reinforces the importance of vigilance on the part of all operating room personnel in its implementation.
AB - Children with myelodysplasia have an increased incidence of latex allergy, which can lead to severe intraoperative allergic reactions. Despite widespread recommendations to avoid intraoperative latex exposure, little evidence exists to support the efficacy of this practice. We examined the incidence of intraoperative allergic reactions in children with myelodysplasia who underwent 1,025 operations in a 36-month period before and after institution of a standardized latex-avoidance protocol. Risk factors for all intraoperative reaction were found to be a history of latex allergy (p = 0.001) and surgery performed before institution of the latex-avoidance protocol (p = 0.01). The estimate of increased risk for allergic reaction was 3.09 times higher in cases performed without latex avoidance. Recognized violation of the protocol after its institution led to severe allergic reactions in three patients. Our experience suggests that a latex avoidance protocol reduces intraoperative allergic reactions in children with myelodysplasia. Development of severe allergic reactions with violation of the protocol reinforces the importance of vigilance on the part of all operating room personnel in its implementation.
KW - Latex allergy
KW - Myelodysplasia
KW - Pediatric anesthesia
KW - Spina bifida
UR - http://www.scopus.com/inward/record.url?scp=0029843566&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029843566&partnerID=8YFLogxK
U2 - 10.1097/01241398-199611000-00018
DO - 10.1097/01241398-199611000-00018
M3 - Article
VL - 16
SP - 799
EP - 802
JO - Journal of Pediatric Orthopaedics
JF - Journal of Pediatric Orthopaedics
SN - 0271-6798
IS - 6
ER -