DOES KAWASAKI DISEASE HAVE A RETROVIRAL AETIOLOGY?

Stanford T. Shulman*, Anne H. Rowley

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

78 Scopus citations

Abstract

In 18 consecutive children with Kawasaki disease of recent onset, reverse transcriptase (RT) activity was studied in co-cultivated peripheral-blood-mononuclear-cell/lymphoblastoid-cell supernatants. 8 of 18 children, but only 1 of 18 controls, showed RT activity in one or more sample (p = 0.009). RT activity was identified in 14 of 226 samples from patients, but in only 1 of 167 from controls (p < 0.01). The findings suggest that a retroviral agent may be casually related to Kawasaki disease.

Original languageEnglish (US)
Pages (from-to)545-546
Number of pages2
JournalThe Lancet
Volume328
Issue number8506
DOIs
StatePublished - Sep 6 1986

ASJC Scopus subject areas

  • Medicine(all)

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