Donor-derived duodenal adenocarcinoma of a bladder-drained pancreas allograft

Dylan Isaacson, Justin Steggerda, Yue Xue, James Wren, Mohammed Javeed Ansari, Gregory B. Auffenberg, Nitin Katariya*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The subset of the population that received bladder-drained allograft pancreata during peak utilization of the technique in the 1990s is approaching 20–30 postoperative years. This time frame is salient, as it parallels the time in which patients in the urologic literature develop adenocarcinomas after bladder reconstruction using gastrointestinal segments. We present the case of a 57-year-old simultaneous pancreas/kidney recipient who presented with microhematuria twenty-four years after transplantation and was found to have an adenocarcinoma of the duodenum of his failed, bladder-drained pancreas. After allograft pancreatectomy/duodenectomy, he remains disease-free eleven months postoperatively. As this patient population ages, practitioners should consider pathology of the donor duodenum and pancreas in recipients who present with gross or microscopic hematuria.

Original languageEnglish (US)
JournalAmerican Journal of Transplantation
DOIs
StateAccepted/In press - 2022

Keywords

  • cancer/malignancy/neoplasia
  • cancer/malignancy/neoplasia: risk factors
  • clinical research/practice
  • pancreas/simultaneous pancreas-kidney transplantation
  • pathology/histopathology
  • urinalysis
  • urology

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

Fingerprint

Dive into the research topics of 'Donor-derived duodenal adenocarcinoma of a bladder-drained pancreas allograft'. Together they form a unique fingerprint.

Cite this