TY - JOUR
T1 - Donor-derived duodenal adenocarcinoma of a bladder-drained pancreas allograft
AU - Isaacson, Dylan
AU - Steggerda, Justin
AU - Xue, Yue
AU - Wren, James
AU - Javeed Ansari, Mohammed
AU - Auffenberg, Gregory B.
AU - Katariya, Nitin
N1 - Funding Information:
Northwestern University Department of Urology Resident Research Fund (DI)
Publisher Copyright:
© 2022 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons.
PY - 2022/9
Y1 - 2022/9
N2 - The subset of the population that received bladder-drained allograft pancreata during peak utilization of the technique in the 1990s is approaching 20–30 postoperative years. This time frame is salient, as it parallels the time in which patients in the urologic literature develop adenocarcinomas after bladder reconstruction using gastrointestinal segments. We present the case of a 57-year-old simultaneous pancreas/kidney recipient who presented with microhematuria twenty-four years after transplantation and was found to have an adenocarcinoma of the duodenum of his failed, bladder-drained pancreas. After allograft pancreatectomy/duodenectomy, he remains disease-free eleven months postoperatively. As this patient population ages, practitioners should consider pathology of the donor duodenum and pancreas in recipients who present with gross or microscopic hematuria.
AB - The subset of the population that received bladder-drained allograft pancreata during peak utilization of the technique in the 1990s is approaching 20–30 postoperative years. This time frame is salient, as it parallels the time in which patients in the urologic literature develop adenocarcinomas after bladder reconstruction using gastrointestinal segments. We present the case of a 57-year-old simultaneous pancreas/kidney recipient who presented with microhematuria twenty-four years after transplantation and was found to have an adenocarcinoma of the duodenum of his failed, bladder-drained pancreas. After allograft pancreatectomy/duodenectomy, he remains disease-free eleven months postoperatively. As this patient population ages, practitioners should consider pathology of the donor duodenum and pancreas in recipients who present with gross or microscopic hematuria.
KW - cancer/malignancy/neoplasia
KW - cancer/malignancy/neoplasia: risk factors
KW - clinical research/practice
KW - pancreas/simultaneous pancreas-kidney transplantation
KW - pathology/histopathology
KW - urinalysis
KW - urology
UR - http://www.scopus.com/inward/record.url?scp=85127441313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85127441313&partnerID=8YFLogxK
U2 - 10.1111/ajt.17042
DO - 10.1111/ajt.17042
M3 - Article
C2 - 35325501
AN - SCOPUS:85127441313
SN - 1600-6135
VL - 22
SP - 2265
EP - 2268
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 9
ER -
