TY - JOUR
T1 - Donor-derived renal allograft mucormycosis in a combined liver and kidney transplantation
T2 - Case report and review of the literature
AU - Thatipelli, Sneha
AU - Santoiemma, Phillip
AU - Echenique, Ignacio A.
AU - Green, Richard
AU - Ison, Michael G.
AU - Ladner, Daniela
AU - Kanwar, Yashpal S.
AU - Stosor, Valentina
N1 - Publisher Copyright:
© 2020 Wiley Periodicals LLC
PY - 2021/6
Y1 - 2021/6
N2 - Mucormycosis infrequently may present with isolated renal involvement. Among solid organ transplant recipients, renal allograft mucormycosis has been most often associated with medical tourism or transplantation outside of the western world. We report a case of an HIV/HCV co-infected woman who underwent simultaneous liver and kidney transplantation with a Public Health Service increased risk donor organ. 16 days after transplant, she developed massive hematuria and was found to have renal allograft Rhizopus spp. involvement, we surmise to have been from donor-derived infection. Therapy included nephrectomy, debridement, liposomal amphotericin B, and posaconazole with survival. We reviewed PubMed indexed, English-language cases of isolated renal mucormycosis in general, in HIV/AIDS, and from donor-derived renal allograft infections.
AB - Mucormycosis infrequently may present with isolated renal involvement. Among solid organ transplant recipients, renal allograft mucormycosis has been most often associated with medical tourism or transplantation outside of the western world. We report a case of an HIV/HCV co-infected woman who underwent simultaneous liver and kidney transplantation with a Public Health Service increased risk donor organ. 16 days after transplant, she developed massive hematuria and was found to have renal allograft Rhizopus spp. involvement, we surmise to have been from donor-derived infection. Therapy included nephrectomy, debridement, liposomal amphotericin B, and posaconazole with survival. We reviewed PubMed indexed, English-language cases of isolated renal mucormycosis in general, in HIV/AIDS, and from donor-derived renal allograft infections.
KW - mucormycosis
KW - renal allograft infection
KW - solid organ transplant recipients
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U2 - 10.1111/tid.13534
DO - 10.1111/tid.13534
M3 - Article
C2 - 33251715
AN - SCOPUS:85106785395
SN - 1398-2273
VL - 23
JO - Transplant Infectious Disease
JF - Transplant Infectious Disease
IS - 3
M1 - e13534
ER -
