Donor-derived Viral Infections in Liver Transplantation

Hannah Nam, Kathy M. Nilles, Josh Levitsky, Michael G. Ison*

*Corresponding author for this work

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Donor-derived infections are defined as any infection present in the donor that is transmitted to 1 or more recipients. Donor-derived infections can be categorized into 2 groups: "expected" and "unexpected" infections. Expected transmissions occur when the donor is known to have an infection, such as positive serology for cytomegalovirus, Epstein Barr virus, or hepatitis B core antibody, at the time of donation. Unexpected transmissions occur when a donor has no known infection before donation, but 1 or more transplant recipients develop an infection derived from the common donor. Unexpected infections are estimated to occur in far less than 1% of solid organ transplant recipients. We will review the epidemiology, risk factors, and approaches to prevention and management of donor-derived viral infectious disease transmission in liver transplantation.

Original languageEnglish (US)
Pages (from-to)1824-1836
Number of pages13
JournalTransplantation
Volume102
Issue number11
DOIs
StatePublished - Nov 1 2018

ASJC Scopus subject areas

  • Transplantation

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