Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection

Navkaranbir S. Bajaj, Christopher Watt, Denis Hadjiliadis, Colin Gillespie, Andrew R. Haas, Alberto Pochettino, James Mendez, Daniel H. Sterman, Lynn M. Schuchter, Jason D. Christie, James C. Lee, Vivek N. Ahya

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Abstract

Summary In the current era of organ shortages and long wait times for life-saving transplants, marginal or extended donors are increasingly being considered; one such category of marginal organs is from donors with a previous history of malignancy. Melanoma in particular has been associated with increased risk of developing late recurrence. In this report, we describe a case of fatal donor melanoma transmission to a 64-year-old lung transplant recipient 32 years after surgical excision of the melanoma. Based on this report and review of the available literature, we conclude that a history of donor melanoma, regardless of the stage and time interval from 'curative' surgical resection, should remain a strong relative contraindication to transplantation.

Original languageEnglish (US)
Pages (from-to)e26-e31
JournalTransplant International
Volume23
Issue number7
DOIs
Publication statusPublished - Jul 1 2010

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Keywords

  • Donor selection criteria
  • Long-term complications
  • Lung transplantation (clinical)
  • Malignancies
  • Organ donation

ASJC Scopus subject areas

  • Transplantation

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