Dopamine, Updated: Reward Prediction Error and Beyond

Talia N. Lerner, Ashley L. Holloway, Jillian L. Seiler

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Dopamine neurons have been intensely studied for their roles in reinforcement learning. A dominant theory of how these neurons contribute to learning is through the encoding of a reward prediction error (RPE) signal. Recent advances in dopamine research have added nuance to RPE theory by incorporating the ideas of sensory prediction error, distributional encoding, and belief states. Further nuance is likely to be added shortly by convergent lines of research on dopamine neuron diversity. Finally, a major challenge is to reconcile RPE theory with other current theories of dopamine function to account for dopamine's role in movement, motivation, and goal-directed planning.

Original languageEnglish (US)
Pages (from-to)123-130
Number of pages8
JournalCurrent opinion in neurobiology
StatePublished - Apr 2021

ASJC Scopus subject areas

  • Neuroscience(all)


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