Dopaminergic modulation of striatal networks in health and Parkinson's disease

D. James Surmeier; Steven M. Graves; Weixing Shen

doi:10.1016/j.conb.2014.07.008

Dopaminergic modulation of striatal networks in health and Parkinson's disease

D. James Surmeier^*, Steven M. Graves, Weixing Shen

^*Corresponding author for this work

Neuroscience

Research output: Contribution to journal › Review article › peer-review

91 Scopus citations

Abstract

In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.

Original language	English (US)
Pages (from-to)	109-117
Number of pages	9
Journal	Current opinion in neurobiology
Volume	29
DOIs	https://doi.org/10.1016/j.conb.2014.07.008
State	Published - Dec 2014

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.conb.2014.07.008

Cite this

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title = "Dopaminergic modulation of striatal networks in health and Parkinson's disease",

abstract = "In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.",

author = "Surmeier, {D. James} and Graves, {Steven M.} and Weixing Shen",

note = "Funding Information: This work was supported by grants from NIH ( NS 34696 and NS 084735 ) and from the IDP and JPB Foundations. ",

year = "2014",

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doi = "10.1016/j.conb.2014.07.008",

language = "English (US)",

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T1 - Dopaminergic modulation of striatal networks in health and Parkinson's disease

AU - Surmeier, D. James

AU - Graves, Steven M.

AU - Shen, Weixing

N1 - Funding Information: This work was supported by grants from NIH ( NS 34696 and NS 084735 ) and from the IDP and JPB Foundations.

PY - 2014/12

Y1 - 2014/12

N2 - In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.

AB - In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.

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DO - 10.1016/j.conb.2014.07.008

M3 - Review article

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JO - Current Opinion in Neurobiology

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ER -

Dopaminergic modulation of striatal networks in health and Parkinson's disease

Abstract

ASJC Scopus subject areas

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